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dc.contributor.author
Schattner, Mirta Ana  
dc.date.available
2021-03-09T21:09:48Z  
dc.date.issued
2018-12-04  
dc.identifier.citation
Schattner, Mirta Ana; Platelet TLR4 at the crossroads of thrombosis and the innate immune response; Federation of American Societies for Experimental Biology; Journal of Leukocyte Biology; 105; 5; 4-12-2018; 873-880  
dc.identifier.issn
0741-5400  
dc.identifier.uri
http://hdl.handle.net/11336/127868  
dc.description.abstract
Platelet TLR-4 activation by pathogen- or damage-associated molecular pattern molecules triggers pro-thrombotic, proinflammatory, and pro-coagulant effector responses. Moreover, platelet TLR4 has a prominent role as a sensor of high lipopolysaccharide circulating levels during sepsis and in the clearance of pathogens mediated by neutrophils. This review presents evidence pointing to TLR4 as a bridge connecting thrombosis and innate immunity.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Federation of American Societies for Experimental Biology  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
HMGB-1  
dc.subject
LPS  
dc.subject
NETS  
dc.subject
PLATELETS  
dc.subject
SEPSIS  
dc.subject
THROMBOSIS  
dc.subject
TLRS  
dc.subject.classification
Bioquímica y Biología Molecular  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Platelet TLR4 at the crossroads of thrombosis and the innate immune response  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-12-22T15:46:45Z  
dc.journal.volume
105  
dc.journal.number
5  
dc.journal.pagination
873-880  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Bethesda  
dc.description.fil
Fil: Schattner, Mirta Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina  
dc.journal.title
Journal of Leukocyte Biology  
dc.relation.isreferencedin
info:eu-repo/semantics/reference/url/http://dx.doi.org/10.1002/ajh.24097  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/JLB.MR0618-213R  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/JLB.MR0618-213R  

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