Mostrar el registro sencillo del ítem
dc.contributor.author
Dedic, Nina
dc.contributor.author
Kühne, Claudia
dc.contributor.author
Jakovcevski, Mira
dc.contributor.author
Hartmann, Jakob
dc.contributor.author
Genewsky, Andreas J.
dc.contributor.author
Gomes, Karina S.
dc.contributor.author
Anderzhanova, Elmira
dc.contributor.author
Pöhlmann, Max L.
dc.contributor.author
Chang, Simon
dc.contributor.author
Kolarz, Adam
dc.contributor.author
Vogl, Annette M.
dc.contributor.author
Dine, Julien
dc.contributor.author
Metzger, Michael W.
dc.contributor.author
Schmid, Bianca
dc.contributor.author
Almada, Rafael C.
dc.contributor.author
Ressler, Kerry J.
dc.contributor.author
Wotjak, Carsten T.
dc.contributor.author
Grinevich, Valery
dc.contributor.author
Chen, Alon
dc.contributor.author
Schmidt, Mathias V.
dc.contributor.author
Wurst, Wolfgang
dc.contributor.author
Refojo, Damian
dc.contributor.author
Deussing, Jan M.
dc.date.available
2021-02-17T16:40:20Z
dc.date.issued
2018-05
dc.identifier.citation
Dedic, Nina; Kühne, Claudia; Jakovcevski, Mira; Hartmann, Jakob; Genewsky, Andreas J.; et al.; Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety; Nature Publishing Group; Nature Neuroscience.; 21; 6; 5-2018; 803-807
dc.identifier.issn
1097-6256
dc.identifier.uri
http://hdl.handle.net/11336/125820
dc.description.abstract
The interplay between corticotropin-releasing hormone (CRH) and the dopaminergic system has predominantly been studied in addiction and reward, while CRH-dopamine interactions in anxiety are scarcely understood. We describe a new population of CRH-expressing, GABAergic, long-range-projecting neurons in the extended amygdala that innervate the ventral tegmental area and alter anxiety following chronic CRH depletion. These neurons are part of a distinct CRH circuit that acts anxiolytically by positively modulating dopamine release.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Nature Publishing Group
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CRH
dc.subject
CRF
dc.subject
depression
dc.subject
behavior
dc.subject.classification
Neurociencias
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-22T17:54:45Z
dc.journal.volume
21
dc.journal.number
6
dc.journal.pagination
803-807
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Dedic, Nina. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Kühne, Claudia. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Jakovcevski, Mira. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Hartmann, Jakob. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Genewsky, Andreas J.. Max Planck Institut Of Psychiatry; Alemania
dc.description.fil
Fil: Gomes, Karina S.. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Anderzhanova, Elmira. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Pöhlmann, Max L.. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Chang, Simon. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Kolarz, Adam. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Vogl, Annette M.. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Dine, Julien. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Metzger, Michael W.. Max Planck Institute of Psychiatry; Armenia
dc.description.fil
Fil: Schmid, Bianca. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Almada, Rafael C.. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Ressler, Kerry J.. Harvard Medical School; Estados Unidos
dc.description.fil
Fil: Wotjak, Carsten T.. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Grinevich, Valery. University of Heidelberg; Alemania
dc.description.fil
Fil: Chen, Alon. Max Planck Institute Of Psychiatry; Alemania
dc.description.fil
Fil: Schmidt, Mathias V.. Institute Of Developmental Genetics, Helmholtz Zentrum; Alemania
dc.description.fil
Fil: Wurst, Wolfgang. German Center for Neurodegenerative Diseases; Alemania
dc.description.fil
Fil: Refojo, Damian. Max Planck Institute Of Psychiatry; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
dc.description.fil
Fil: Deussing, Jan M.. Max Planck Institute Of Psychiatry; Alemania
dc.journal.title
Nature Neuroscience.
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1038/s41593-018-0151-z
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41593-018-0151-z
Archivos asociados
Tamaño:
1.798Mb
Formato:
PDF