Artículo
Mathematical models: a precious tool for research in physiology
Fecha de publicación:
03/2015
Editorial:
Sociedad Argentina de Fisiología
Revista:
Physiological Mini Reviews
e-ISSN:
1669-5410
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The use of mathematical models in science has increased in the last decades, since it is clear that they constitute an essential tool for the progress of experimental research. The main goal of this review is to present to the experimental physiologists some background on the different steps that are usually followed to develop a model. Probably more important, we aim to provide some basic thoughts to highlight the importance and need of mathematical modeling for scientific discovery and progress. The review also recapitulates the evolution of myocyte and Ca2+ handling models, the parallel work done in the interpretation of cardiac force generation, the integration of myocyte and force models into mechano-electric representations, and the construction of multi-scale models by assembling ventricular models with the mathematical descriptions of the circulatory system.
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Identificadores
Colecciones
Articulos(CIC)
Articulos de CENTRO DE INVEST.CARDIOVASCULARES (I)
Articulos de CENTRO DE INVEST.CARDIOVASCULARES (I)
Citación
Lascano, Elena C.; Mattiazzi, Ramona Alicia; Negroni, Jorge A.; Mathematical models: a precious tool for research in physiology; Sociedad Argentina de Fisiología; Physiological Mini Reviews; 8; 2; 3-2015; 12-22
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