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dc.contributor.author
Chicco, Adriana Graciela
dc.contributor.author
D'alessandro, Maria Eugenia Guadalupe
dc.contributor.author
Hein, Gustavo Juan
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Oliva, Maria Eugenia
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Lombardo, Yolanda B.
dc.date.available
2020-02-14T20:56:25Z
dc.date.issued
2009-12
dc.identifier.citation
Chicco, Adriana Graciela; D'alessandro, Maria Eugenia Guadalupe; Hein, Gustavo Juan; Oliva, Maria Eugenia; Lombardo, Yolanda B.; Dietary chia seed (Salvia hispanica L.) rich in a-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats; Cambridge University Press; British Journal of Nutrition; 101; 1; 12-2009; 41-50
dc.identifier.issn
0007-1145
dc.identifier.uri
http://hdl.handle.net/11336/97696
dc.description.abstract
The present study investigates the benefits of the dietary intake of chia seed (Salvia hispanica L.) rich in α-linolenic acid and fibre upon dyslipidaemia and insulin resistance (IR), induced by intake of a sucrose-rich (62.5 %) diet (SRD). To achieve these goals two sets of experiments were designed: (i) to study the prevention of onset of dyslipidaemia and IR in Wistar rats fed during 3 weeks with a SRD in which chia seed was the dietary source of fat; (ii) to analyse the effectiveness of chia seed in improving or reversing the metabolic abnormalities described above. Rats were fed a SRD during 3 months; by the end of this period, stable dyslipidaemia and IR were present in the animals. From months 3-5, half the animals continued with the SRD and the other half were fed a SRD in which the source of fat was substituted by chia seed (SRD+chia). The control group received a diet in which sucrose was replaced by maize starch. The results showed that: (i) dietary chia seed prevented the onset of dyslipidaemia and IR in the rats fed the SRD for 3 weeks - glycaemia did not change; (ii) dyslipidaemia and IR in the long-term SRD-fed rats were normalised without changes in insulinaemia when chia seed provided the dietary fat during the last 2 months of the feeding period. Dietary chia seed reduced the visceral adiposity present in the SRD rats. The present study provides new data regarding the beneficial effect of chia seed upon lipid and glucose homeostasis in an experimental model of dislipidaemia and IR.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Cambridge University Press
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
DIETARY CHIA SEED
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DYSLIPIDAEMIA
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INSULIN RESISTANCE
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SUCROSE-RICH DIETS
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Fisiología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Dietary chia seed (Salvia hispanica L.) rich in a-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-02-13T18:54:59Z
dc.journal.volume
101
dc.journal.number
1
dc.journal.pagination
41-50
dc.journal.pais
Reino Unido
dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Chicco, Adriana Graciela. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Ciencias Biológicas; Argentina
dc.description.fil
Fil: D'alessandro, Maria Eugenia Guadalupe. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Ciencias Biológicas; Argentina
dc.description.fil
Fil: Hein, Gustavo Juan. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Ciencias Biológicas; Argentina
dc.description.fil
Fil: Oliva, Maria Eugenia. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Ciencias Biológicas; Argentina
dc.description.fil
Fil: Lombardo, Yolanda B.. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Departamento de Ciencias Biológicas; Argentina
dc.journal.title
British Journal of Nutrition
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://journals.cambridge.org
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1017/S000711450899053X
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