Artículo
Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
Rodriguez-Tudela, Juan Luis; Gomez-Lopez, Alicia; Arendrup, Maiken C.; Garcia, Guillermo Manuel
; Perlin, David S.; Lass-Flörl, Cornelia; Cuenca-Estrella, Manuel
; Perlin, David S.; Lass-Flörl, Cornelia; Cuenca-Estrella, Manuel
Fecha de publicación:
07/2010
Editorial:
American Society for Microbiology
Revista:
Antimicrobial Agents and Chemotherapy
ISSN:
0066-4804
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
According to the product insert for Cancidas (caspofungin acetate), the drug must not be diluted in solutions containing glucose as this decreases caspofungin stability. The aim of this study was to compare caspofungin MICs for a collection of yeasts by means of EUCAST method EDef7.1 but using two different concentrations of glucose: 2% versus 0.2%. MICs were identical or within one 2-fold dilution for 93 out of 95 strains (97.9%), showing that glucose does not interfere with susceptibility.
Palabras clave:
Echinocandinas
,
Resistencia
,
Evaluación sensibilidad
,
Caspofungina
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Licencia
Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción:
Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
Colecciones
Articulos(CCT - SANTA FE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Citación
Rodriguez-Tudela, Juan Luis; Gomez-Lopez, Alicia; Arendrup, Maiken C.; Garcia, Guillermo Manuel; Perlin, David S.; et al.; Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 54; 7; 7-2010; 3056-3057
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