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dc.contributor.author
Dallard, Bibiana Elisabet
dc.contributor.author
Baravalle, Celina
dc.contributor.author
Ortega, Hugo Hector
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Tumini, M.
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Canavesio, V.R.
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Neder, V.E.
dc.contributor.author
Calvinho, Luis Fernando
dc.date.available
2020-02-14T19:32:40Z
dc.date.issued
2009-12
dc.identifier.citation
Dallard, Bibiana Elisabet; Baravalle, Celina; Ortega, Hugo Hector; Tumini, M.; Canavesio, V.R.; et al.; Effect of a biological response modifier on expression of CD14 receptor and tumor necrosis factor-alpha in Staphylococcus aureus-infected mammary glands at drying off; Elsevier Science; Veterinary Immunology And Immunopathology; 132; 2-4; 12-2009; 237-242
dc.identifier.issn
0165-2427
dc.identifier.uri
http://hdl.handle.net/11336/97602
dc.description.abstract
Agents that increase natural protective mechanisms have been proposed for prevention and treatment of intramammary infections. The objectives of this study were to get an insight of innate immune mechanisms that occur during bovine mammary involution in both uninfected and chronically Staphylococcus aureus-infected glands and to describe the effects on those mechanisms of a single intramammary infusion of a LPS-based biological response modifier (BRM) at the end of lactation. Three groups of 12 cows, each one including 6 S. aureus-infected and 6 uninfected, were infused in two mammary quarters with BRM or placebo and sacrificed at 7, 14 and 21 d of involution. In uninfected and S. aureus-infected quarters treated with a BRM, the number of monocytes/macrophages detected with CD14 antibody was significantly higher (P < 0.05) than in placebo-treated quarters at every sampling evaluation period. In uninfected quarters, the TNF-α staining area was not affected by BRM treatment. However, in infected quarters, the immunostained area for TNF-α was significantly higher than in uninfected quarters and BRM treatment was associated with increased staining at 21 d of involution.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BIOLOGICAL RESPONSE MODIFIER
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BOVINE MAMMARY GLAND
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CD14 RECEPTOR
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STAPHYLOCOCCUS AUREUS
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TNF-Α
dc.subject.classification
Ciencias Veterinarias
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Ciencias Veterinarias
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CIENCIAS AGRÍCOLAS
dc.title
Effect of a biological response modifier on expression of CD14 receptor and tumor necrosis factor-alpha in Staphylococcus aureus-infected mammary glands at drying off
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-02-13T18:55:28Z
dc.journal.volume
132
dc.journal.number
2-4
dc.journal.pagination
237-242
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Dallard, Bibiana Elisabet. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Baravalle, Celina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Litoral; Argentina
dc.description.fil
Fil: Ortega, Hugo Hector. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Litoral; Argentina
dc.description.fil
Fil: Tumini, M.. Universidad Nacional del Litoral; Argentina
dc.description.fil
Fil: Canavesio, V.R.. Instituto Nacional de Tecnología Agropecuaria Eea, Rafaela; Argentina
dc.description.fil
Fil: Neder, V.E.. Instituto Nacional de Tecnología Agropecuaria Eea, Rafaela; Argentina
dc.description.fil
Fil: Calvinho, Luis Fernando. Universidad Nacional del Litoral; Argentina. Instituto Nacional de Tecnología Agropecuaria Eea, Rafaela; Argentina
dc.journal.title
Veterinary Immunology And Immunopathology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://sciencedirect.com/science/journal/01652427
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.vetimm.2009.05.004
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