Artículo
Matricellular proteins and inflammatory cells: A task force to promote or defeat cancer?
Fecha de publicación:
02/2010
Editorial:
Elsevier
Revista:
Cytokine & Growth Factor Reviews
ISSN:
1359-6101
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
In the last years it became clear that the tumor microenvironment plays a major role in neoplastic growth. Proteins secreted either by the malignant cells or by the tumor-associated stromal cells act as extracellular signal transductors, orchestrating tumor progression. Sentinel cells of the innate immune system patrol the different organs and have proven either to promote tumor growth or induce tumor suppression. In recent years, members of the matricellular family of extracellular proteins were shown to be involved in different aspects of the inflammatory response during tumor development, although in contradictory ways. In this review we discuss the evidence available up to date that relates matricellular proteins with the regulation of the inflammatory response and tumor progression.
Palabras clave:
CANCER
,
INFLAMMATION
,
MATRICELLULAR PROTEINS
,
SPARC
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(IIBBA)
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)
Citación
Llera, Andrea Sabina; Girotti, Maria Romina; Benedetti, Lorena Gabriela; Podhajcer, Osvaldo Luis; Matricellular proteins and inflammatory cells: A task force to promote or defeat cancer?; Elsevier; Cytokine & Growth Factor Reviews; 21; 1; 2-2010; 67-76
Compartir
Altmétricas