Artículo

N-demethyl-sauroxine, a novel Lycodine Group alkaloid from Huperzia saururus

Vallejo, Mariana GuadalupeIcon ; Ortega, María GabrielaIcon ; Cabrera, Jose LuisIcon ; Agnese, Mariel
Fecha de publicación: 07/2013
Editorial: Elsevier
Revista: Tetrahedron Letters
ISSN: 0040-4039
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The present study describes the isolation and identification of N-demethyl-sauroxine, a novel Lycopodium alkaloid obtained from Huperzia saururus (Lam.) Trevis. (Lycopodiaceae). Its structure and relative stereochemistry were elucidated on the basis of its spectral data and chemical correlations. Additionally, acetylcholinesterase inhibitory activity was evaluated (IC50 = 209.6 ± 1.1 lM). The structure of the already identified alkaloid sauroxine was also re-validated through two dimensional NMR data.
Palabras clave: Huperzia Saururus , N-Demethyl-Sauroxine , Acetylcholinesterase Inhibition , Sauroxine Nmr Two Dimensional Data
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Atribución-NoComercial-SinDerivadas 2.5 Argentina (CC BY-NC-ND 2.5 AR)
Identificadores
URI: http://hdl.handle.net/11336/9663
DOI: http://dx.doi.org/10.1016/j.tetlet.2013.07.068
URL: http://www.sciencedirect.com/science/article/pii/S0040403913012173
Colecciones
Articulos(CCT - CORDOBA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Articulos(IMBIV)
Articulos de INST.MULTIDISCIPL.DE BIOLOGIA VEGETAL (P)
Citación
Vallejo, Mariana Guadalupe; Ortega, María Gabriela; Cabrera, Jose Luis; Agnese, Mariel; N-demethyl-sauroxine, a novel Lycodine Group alkaloid from Huperzia saururus; Elsevier; Tetrahedron Letters; 54; 38; 7-2013; 5197-5200
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