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dc.contributor.author
Echavarria, M.  
dc.contributor.author
Herrera, Fabian Armando  
dc.contributor.author
Solimano, J.  
dc.contributor.author
Villamea, L.  
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Riera, L.  
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de Klerk, E. P. A.  
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Kroes, A. C. M.  
dc.contributor.author
Carballal, Guadalupe  
dc.date.available
2020-01-29T20:50:58Z  
dc.date.issued
2003-02  
dc.identifier.citation
Echavarria, M.; Herrera, Fabian Armando; Solimano, J.; Villamea, L.; Riera, L.; et al.; Cyclic recovery of adenovirus in a stem cell transplant recipient: An inverse association with graft-versus-host disease; Nature Publishing Group; Bone Marrow Transplantation; 31; 4; 2-2003; 301-303  
dc.identifier.issn
0268-3369  
dc.identifier.uri
http://hdl.handle.net/11336/96177  
dc.description.abstract
Adenovirus (AdV) infections have been increasingly recognized as significant pathogens that may cause severe morbidity and mortality among stem cell transplant (SCT) recipients. AdV can cause localized infections such as hemorrhagic cystitis (HC), pneumonia, hepatitis and also disseminated disease that can lead to death. We report a case of severe hemorrhagic cystitis in a SCT recipient who died 83 days after transplant. In this patient, AdV recovery was not constantly detected. In fact, fluctuations of the AdV detection in leukocytes and urine were observed by culture and PCR. When analyzing this viral cyclic recovery with different signs or symptoms in the patient, we observed an inverse association with the presence of acute graft-versus-host disease (GVHD). Whether these fluctuations represent donor-derived reactivity, indirectly manifested by the presence of GVHD, requires further study. This is the first case describing a dynamic pattern of AdV replication in leukocytes and urine samples from a patient with severe HC and the temporal correlation with GVHD.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Nature Publishing Group  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ADENOVIRUS  
dc.subject
CYCLIC RECOVERY  
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GRAFT-VERSUS-HOST DISEASE  
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HEMORRHAGIC CYSTITIS  
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STEM CELL TRANSPLANTATION  
dc.subject.classification
Trasplantes  
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Medicina Clínica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Cyclic recovery of adenovirus in a stem cell transplant recipient: An inverse association with graft-versus-host disease  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-01-29T15:41:00Z  
dc.journal.volume
31  
dc.journal.number
4  
dc.journal.pagination
301-303  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Echavarria, M.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina  
dc.description.fil
Fil: Herrera, Fabian Armando. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina  
dc.description.fil
Fil: Solimano, J.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina  
dc.description.fil
Fil: Villamea, L.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina  
dc.description.fil
Fil: Riera, L.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina  
dc.description.fil
Fil: de Klerk, E. P. A.. Leiden University Medical Center; Países Bajos  
dc.description.fil
Fil: Kroes, A. C. M.. Leiden University Medical Center; Países Bajos  
dc.description.fil
Fil: Carballal, Guadalupe. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
Bone Marrow Transplantation  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/1703814  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1038/sj.bmt.1703814