Artículo
Kinetics and binding properties of cloramphenicol imprinted polymers
Fecha de publicación:
04/2007
Editorial:
Elsevier Science
Revista:
Journal of Non-crystalline Solids
ISSN:
0022-3093
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Molecularly imprinted polymers (MIPs) are easily obtained by a non-covalent approach through the copolymerisation of suitable functional monomers and cross-linkers in the presence of the print molecule. Removal of the template leaves a polymer that selectively recognises it. However, experimental data have demonstrated that non-covalent molecularly imprinted polymers exhibit a heterogeneous binding sites distribution. In this work, two different imprinted polymers for chloramphenicol (CAP), obtained using different template concentrations, were evaluated for their kinetics and affinity binding properties against CAP in a batch approach. Experimental binding isotherms were fitted to Langmuir, Freundlich and Langmuir-Freundlich isotherms and the affinity distribution corresponding to the Freundlich isotherm was used to extract binding parameters. Parallel studies were performed for the binding of chloramphenicol diacetate to the CAP-imprinted polymers.
Palabras clave:
ADSORPTION
,
PHARMACEUTICALS
,
POLYMERS AND ORGANICS
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(IQUIBICEN)
Articulos de INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CS. EXACTAS Y NATURALES
Articulos de INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CS. EXACTAS Y NATURALES
Citación
Corton, Eduardo; García Calzón, J. A.; Díaz García, M. E.; Kinetics and binding properties of cloramphenicol imprinted polymers; Elsevier Science; Journal of Non-crystalline Solids; 353; 8-10; 4-2007; 974-980
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