Artículo
Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
Di Ciaccio, Lucía Soledad
; Spotorno, V.G.; Córdoba Estévez, M.M.; Ríos, D.J.L.; Fortunato, Renée Hersilia
; Salvat, Adriana Elisabeth
Fecha de publicación:
03/2018
Editorial:
Wiley Blackwell Publishing, Inc
Revista:
Letters in Applied Microbiology
ISSN:
0266-8254
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Fungi are cosmopolitan organisms that grow in and adapt to a vast number of substrates and environments, and that can cause diseases in humans and animals, as well as in crops. The vast area and diverse geographical characteristics of Argentina, with the consequent climatic diversity make the country an important source of biological resources suitable for the search of new compounds. The aim of the present study was to describe the antifungal activity of extracts of Parastrephia quadrangularis, a species from northern Argentina, against Fusarium verticillioides M7075. Bio‐guided fractionation and MS/MS studies were conducted to elucidate the chemical structure of active compounds. The extracts exhibited a minimum inhibitory concentration among 118·74 and 250 μg ml−1 and the differences between the treatments and the inoculum control was 12·5–16·5 mm, respectively, in colony growth. Moreover, hyphae treated with the extracts stained blue with Evans blue, showed alterations in permeability of plasma membranes. HLPC‐MS analysis of active fractions revealed the presence of p‐coumaroyloxitremetone, and a derivate structure for another compound is proposed. Significance and Impact of the Study In Argentina, Fusarium verticillioides causes ‘ear rot’, a disease that produces important yield and nutritional quality losses in the maize producing region. This study suggests that Parastrephia quadrangularis extracts have potential for the growth inhibition against F. verticillioides M7075, and the bioactivity is reported for the first time. The results obtained will provide a starting point for discover new antimicotic candidate in natural products.
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Di Ciaccio, Lucía Soledad; Spotorno, V.G.; Córdoba Estévez, M.M.; Ríos, D.J.L.; Fortunato, Renée Hersilia; et al.; Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides; Wiley Blackwell Publishing, Inc; Letters in Applied Microbiology; 66; 3; 3-2018; 244-251
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