Mostrar el registro sencillo del ítem
dc.contributor.author
Tittarelli, Estefanía
dc.contributor.author
Barrero, Paola Roxana
dc.contributor.author
Mistchenko, Alicia Susana
dc.contributor.author
Valinotto, Laura Elena
dc.date.available
2020-01-14T17:47:34Z
dc.date.issued
2016-01
dc.identifier.citation
Tittarelli, Estefanía; Barrero, Paola Roxana; Mistchenko, Alicia Susana; Valinotto, Laura Elena; Secondary dengue virus infections during the 2009 outbreak in Buenos Aires; Wiley Blackwell Publishing, Inc; Tropical Medicine And International Health; 21; 1; 1-2016; 28-32
dc.identifier.issn
1360-2276
dc.identifier.uri
http://hdl.handle.net/11336/94619
dc.description.abstract
Objectives: To evaluate the occurrence of secondary dengue virus (DENV) infections during the 2009 outbreak in a non-endemic area. Viral loads were evaluated in serum from acute-phase patients, comparing primary and secondary infection. Methods: Serum samples from patients with clinical diagnosis of suspected dengue were referred to the Virology Laboratory at 'Ricardo Gutiérrez' Children's Hospital. Dengue-positive samples were classified as primary or secondary DENV infections through serological methods (anti-DENV IgM and IgG). Viral loads were measured by quantitative real-time PCR (qRT-PCR) in samples obtained in the first 5 days of infection. Statistical analyses were performed to evaluate factors that might correlate with differences in the viral load of primary or secondary infection. Results: A total of 229 DENV cases were confirmed; among them, 22.7% were secondary infections. No significant differences were found between the viral load of primary and secondary infections. Conclusion: We detected a high percentage of secondary DENV infections in a non-endemic area; this finding might correspond to socio-demographic characteristics of the group under study or indicate a previous cryptic DENV circulation causing inapparent infections.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
DENGUE VIRUS
dc.subject
SECONDARY INFECTIONS
dc.subject
VIRAL LOAD
dc.subject.classification
Virología
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Secondary dengue virus infections during the 2009 outbreak in Buenos Aires
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-12-27T14:01:26Z
dc.journal.volume
21
dc.journal.number
1
dc.journal.pagination
28-32
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Tittarelli, Estefanía. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez". Laboratorio de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Barrero, Paola Roxana. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez". Laboratorio de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Mistchenko, Alicia Susana. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez". Laboratorio de Virología; Argentina
dc.description.fil
Fil: Valinotto, Laura Elena. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez". Laboratorio de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Tropical Medicine And International Health
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/tmi.12619
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/tmi.12619
Archivos asociados