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dc.contributor.author
Gadan, M.A.  
dc.contributor.author
González, Sara Josefina  
dc.contributor.author
Batalla, M.  
dc.contributor.author
Olivera, M.S.  
dc.contributor.author
Policastro, Lucia Laura  
dc.contributor.author
Sztejnberg, M.L.  
dc.date.available
2020-01-14T15:22:44Z  
dc.date.issued
2015-10  
dc.identifier.citation
Gadan, M.A.; González, Sara Josefina; Batalla, M.; Olivera, M.S.; Policastro, Lucia Laura; et al.; Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 104; 10-2015; 155-159  
dc.identifier.issn
0969-8043  
dc.identifier.uri
http://hdl.handle.net/11336/94607  
dc.description.abstract
In the frame of the Argentine BNCT Project a new research line has been started to study the application of BNCT to the treatment of locoregional recurrences of HER2+ breast cancer subtype. Based on former studies, the strategy considers the use of immunoliposomes as boron carriers nanovehicles to target HER2 overexpressing cells. The essential concerns of the current stage of this proposal are the development of carriers that can improve the efficiency of delivery of boron compounds and the dosimetric assessment of treatment feasibility. For this purpose, an specific pool of clinical cases that can benefit from this application was determined. In this work, we present the proposal and the advances related to the different stages of current research.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Pergamon-Elsevier Science Ltd  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
HER2-ENRICHED BREAST CANCER  
dc.subject
IMMUNOLIPOSOMES  
dc.subject
POST TREATMENT RECURRENCES  
dc.subject.classification
Otras Ciencias de la Salud  
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Ciencias de la Salud  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2019-12-27T14:01:39Z  
dc.journal.volume
104  
dc.journal.pagination
155-159  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Gadan, M.A.. Comisión Nacional de Energía Atómica; Argentina  
dc.description.fil
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Batalla, M.. Comisión Nacional de Energía Atómica; Argentina  
dc.description.fil
Fil: Olivera, M.S.. Comisión Nacional de Energía Atómica; Argentina  
dc.description.fil
Fil: Policastro, Lucia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina  
dc.description.fil
Fil: Sztejnberg, M.L.. Comisión Nacional de Energía Atómica; Argentina  
dc.journal.title
Applied Radiation and Isotopes  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804315300877  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.apradiso.2015.07.006