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dc.contributor.author
Auad, Jordana
dc.contributor.author
Cerutti, Julieta
dc.contributor.author
Cooper, Laura Gabriela
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dc.contributor.author
Camussone, Cecilia María
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Lozano, Natalia A.
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Crespo, Francisco M.
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Lozano, Alejandro
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dc.date.available
2019-12-18T00:05:40Z
dc.date.issued
2018-01
dc.identifier.citation
Auad, Jordana; Cerutti, Julieta; Cooper, Laura Gabriela; Camussone, Cecilia María; Lozano, Natalia A.; et al.; Humoral immune response of pregnant goats to two Corynebacterium pseudotuberculosis bacterin formulations; Universidad Austral de Chile; Austral Journal of Veterinary Sciences; 50; 1-2018; 101-105
dc.identifier.issn
0719-8000
dc.identifier.uri
http://hdl.handle.net/11336/92456
dc.description.abstract
Caseous lymphadenitis is a chronic suppurative bacterial disease caused by Corynebacterium pseudotuberculosis with a high prevalence in small ruminants. Different vaccine preparations have been employed to control this disease. The adjuvant used in the formulation is a critical factor for the improvement of vaccine efficacy. No commercial vaccines are available in Argentina. The aims of the present work were to compare the specific antibody response against a C. pseudotuberculosis whole cell vaccine formulated with a classical and an immunoestimulant adjuvant in pregnant goats, and to assess the transfer of vaccine- specific antibodies from the goat to the offspring through colostrum. Twenty three pregnant goats were vaccinated. The animals were randomly allocated to three groups: control, aluminum hydroxide Al(OH)3 adjuvant and a new cage-like particle adjuvant (ISPA). Antibodies (IgG) against this antigen were measured by ELISA. A robust humoral immune response was detected in vaccinated animals, with production of specific IgG, without finding significant differences between the vaccines formulated with different adjuvants. High levels of specific antibodies were detected in colostrum samples from both immunized groups, which were passively transfered from goats to offprings. No adverse local reactions in the vaccines injection sites were detected.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Universidad Austral de Chile
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ISPA adjuvant
dc.subject
Immunoglobulin G
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Colostrum
dc.subject.classification
Ciencias Veterinarias
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dc.subject.classification
Ciencias Veterinarias
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dc.subject.classification
CIENCIAS AGRÍCOLAS
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dc.title
Humoral immune response of pregnant goats to two Corynebacterium pseudotuberculosis bacterin formulations
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-28T16:52:07Z
dc.journal.volume
50
dc.journal.pagination
101-105
dc.journal.pais
Chile
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dc.description.fil
Fil: Auad, Jordana. Universidad Católica de Córdoba; Argentina
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Fil: Cerutti, Julieta. Universidad Católica de Córdoba; Argentina
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Fil: Cooper, Laura Gabriela. Universidad Católica de Córdoba; Argentina
dc.description.fil
Fil: Camussone, Cecilia María. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
dc.description.fil
Fil: Lozano, Natalia A.. Universidad Católica de Córdoba; Argentina
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Fil: Crespo, Francisco M.. Establecimiento Los Talas. Potrero de Garay, Córdoba; Argentina
dc.description.fil
Fil: Lozano, Alejandro. Universidad Católica de Córdoba; Argentina
dc.journal.title
Austral Journal of Veterinary Sciences
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://revistas.uach.cl/index.php/australjvs/article/view/2961
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