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dc.contributor.author
Ferraz, Tiago
dc.contributor.author
Rossoni, Daniela M.
dc.contributor.author
Althoff, Sérgio L.
dc.contributor.author
Pissinatti, Alcides
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Paixão Cortês, Vanessa R.
dc.contributor.author
Bortolini, María Cátira
dc.contributor.author
González José, Rolando
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Marroig, Gabriel
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Salzano, Francisco M.
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Gonçalves, Gislene L.
dc.contributor.author
Hünemeier, Tábita
dc.date.available
2019-12-05T17:15:45Z
dc.date.issued
2018-12
dc.identifier.citation
Ferraz, Tiago; Rossoni, Daniela M.; Althoff, Sérgio L.; Pissinatti, Alcides; Paixão Cortês, Vanessa R.; et al.; Contrasting patterns of RUNX2 repeat variations are associated with palate shape in phyllostomid bats and New World primates; Nature Publishing Group; Scientific Reports; 8; 1; 12-2018; 1-10
dc.identifier.issn
2045-2322
dc.identifier.uri
http://hdl.handle.net/11336/91494
dc.description.abstract
Establishing the genetic basis that underlies craniofacial variability in natural populations is one of the main topics of evolutionary and developmental studies. One of the genes associated with mammal craniofacial variability is RUNX2, and in the present study we investigated the association between craniofacial length and width and RUNX2 across New World bats (Phyllostomidae) and primates (Catarrhini and Platyrrhini). Our results showed contrasting patterns of association between the glutamate/alanine ratios (Q/A ratio) and palate shape in these highly diverse groups. In phyllostomid bats, we found an association between shorter/broader faces and increase of the Q/A ratio. In New World monkeys (NWM) there was a positive correlation of increasing Q/A ratios to more elongated faces. Our findings reinforced the role of the Q/A ratio as a flexible genetic mechanism that would rapidly change the time of skull ossification throughout development. However, we propose a scenario in which the influence of this genetic adjustment system is indirect. The Q/A ratio would not lead to a specific phenotype, but throughout the history of a lineage, would act along with evolutionary constraints, as well as other genes, as a facilitator for adaptive morphological changes.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Nature Publishing Group
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BATS
dc.subject
NEW WORLD PRIMATES
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RUNX2
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MORPHOLOGICAL INTEGRATION
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Genética y Herencia
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Contrasting patterns of RUNX2 repeat variations are associated with palate shape in phyllostomid bats and New World primates
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-22T15:06:15Z
dc.journal.volume
8
dc.journal.number
1
dc.journal.pagination
1-10
dc.journal.pais
Reino Unido
dc.description.fil
Fil: Ferraz, Tiago. Universidade Federal do Rio Grande do Sul; Brasil. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Rossoni, Daniela M.. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Althoff, Sérgio L.. Universidade Regional de Blumenau; Brasil
dc.description.fil
Fil: Pissinatti, Alcides. Universidade Federal da Bahia; Brasil
dc.description.fil
Fil: Paixão Cortês, Vanessa R.. Centro de Primatologia do Rio de Janeiro; Brasil
dc.description.fil
Fil: Bortolini, María Cátira. Universidade Federal do Rio Grande do Sul; Brasil
dc.description.fil
Fil: González José, Rolando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico de Ciencias Sociales y Humanas; Argentina
dc.description.fil
Fil: Marroig, Gabriel. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; Brasil
dc.description.fil
Fil: Gonçalves, Gislene L.. Universidad de Tarapacá de Arica; Chile. Universidade Federal do Rio Grande do Sul; Brasil
dc.description.fil
Fil: Hünemeier, Tábita. Universidade de Sao Paulo; Brasil
dc.journal.title
Scientific Reports
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1038/s41598-018-26225-7
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41598-018-26225-7
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