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dc.contributor.author
Davico, Carla Eliana
dc.contributor.author
Loteste, Alicia Elena
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Parma, Maria Julieta E.
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Poletta, Gisela Laura
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Simoniello, Maria Fernanda
dc.date.available
2019-11-12T21:45:45Z
dc.date.issued
2018-09
dc.identifier.citation
Davico, Carla Eliana; Loteste, Alicia Elena; Parma, Maria Julieta E.; Poletta, Gisela Laura; Simoniello, Maria Fernanda; Stress oxidative and genotoxicity in Prochilodus lineatus (Valenciennes, 1836) exposed to commercial formulation of insecticide cypermethrin; Taylor & Francis; Drug And Chemical Toxicology; 9-2018; 1-6
dc.identifier.issn
0148-0545
dc.identifier.uri
http://hdl.handle.net/11336/88689
dc.description.abstract
The use of toxic pesticides has become a world problem because they can contaminate streams and rivers, producing an adverse impact on non-target aquatic biota, including fishes. Cypermethrin is one of the most important insecticides to control ectoparasites in wide-scale. The aim of this study was to evaluate the effect of commercial formulations of cypermethrin, SHERPA O (0.0, 0.075, 0.15, and 0.3 mg/L of cypermethrin) in fish Prochilodus lineatus for 96 h in semi-static condition, using biomarkers of genotoxicity:micronucleus frequency (MNF) in erythrocytes and biomarkers of oxidative damage: lipid peroxidation (TBARS) and antioxidant defenses, catalase (CAT) and glutathione (GSH) in liver tissue. Our results showed a significant decrease (p<0.05) of CAT at pesticide concentrations of 0.150 and 0.300 lg/L, but no significant difference was observed in TBARS or GSH in any exposed group(p>0.05) in comparison to the control. A significant increase was observed in the MNF in the group exposed to 0.3 lg/L of cypermethrin compared to negative control (p<0.05). Finally, P. lineatus proved to be a sensitive species to the commercial formulations of cypermethrin and that CAT and MNF are effective indicators of these toxic effects
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
FISH
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LIVE TISSUE
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BIOMARKERS
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CATALASE
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Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Stress oxidative and genotoxicity in Prochilodus lineatus (Valenciennes, 1836) exposed to commercial formulation of insecticide cypermethrin
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-25T18:53:11Z
dc.journal.pagination
1-6
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Londres
dc.description.fil
Fil: Davico, Carla Eliana. Universidad Nacional del Litoral; Argentina
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Fil: Loteste, Alicia Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto Nacional de Limnología. Universidad Nacional del Litoral. Instituto Nacional de Limnología; Argentina
dc.description.fil
Fil: Parma, Maria Julieta E.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto Nacional de Limnología. Universidad Nacional del Litoral. Instituto Nacional de Limnología; Argentina
dc.description.fil
Fil: Poletta, Gisela Laura. Universidad Nacional del Litoral; Argentina
dc.description.fil
Fil: Simoniello, Maria Fernanda. Universidad Nacional del Litoral; Argentina
dc.journal.title
Drug And Chemical Toxicology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/loi/idct20
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/01480545.2018.1497643
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