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dc.contributor.author
Díaz, Alejandro
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Zócalo, Yanina
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Bia, Daniel
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Sabino, Franco
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Rodríguez, Victoria
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Cabrera Fischer, Edmundo Ignacio
dc.date.available
2019-10-31T18:08:30Z
dc.date.issued
2019-02
dc.identifier.citation
Díaz, Alejandro; Zócalo, Yanina; Bia, Daniel; Sabino, Franco; Rodríguez, Victoria; et al.; Reference intervals of aortic pulse wave velocity assessed with an oscillometric device in healthy children and adolescents from Argentina; Taylor & Francis; Clinical and Experimental Hypertension; 41; 2; 2-2019; 101-112
dc.identifier.issn
1064-1963
dc.identifier.uri
http://hdl.handle.net/11336/87748
dc.description.abstract
Age-related reference intervals (RIs) of aortic pulse wave velocity (Ao-PWV) obtained from a large healthy population are lacking in South America. The aims of this study were to determine Ao-PWV RIs in a cohort of healthy children and adolescents from Argentina and to generate year-to-year percentile curves. Ao-PWV was measured in 1000 healthy subjects non-exposed to traditional cardiovascular risk factors (Age: 10–22 y. o., 56% males). First, we evaluated if RIs for males and females were necessaries (correlation and covariate analysis). Second, mean (M) and standard deviation (SD) age-related equations were obtained for cf-PWV, using parametric regression methods based on fractional polynomials. Third, age-specific (year to year) percentiles curves (for all, males and females children and adolescents) were generated using the standard normal distribution. They were, age-specific 1st, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th and 99th percentile curves and values. After covariate analysis (i.e., adjusting by age, jugulum-symphysis distance, body weight and height), specific RIs for males and females of children and adolescents were evidenced as necessaries. The equations were For all subjects: Ao-PWV_Mean = 4.98 + 12.86x10 −5 Age 3 . Ao-PWV_SD = 0.47 + 21.00x10 −6 Age 3 . For girls: Ao-PWV_Mean = 5.07 + 10.23x10 −5 Age 3 . Ao-PWV_SD = 0.50 + 10.00x10 −6 Age 3 . For boys: Ao-PWV_Mean = 4.87 + 15.81x10 −5 Age 3 . Ao-PWV_SD = 0.46 + 22.34x10 −6 Age 3 . Our study provides the largest database to-date concerning Ao-PWV in healthy children and adolescents in Argentina. Age-related equations (M and SD values) for Ao-PWV are reported by the first time. Specific RIs and percentiles of Ao-PWV are now available according to age and sex for an Argentinian population.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ADOLESCENTS
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AORTIC PULSE WAVE VELOCITY
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ARTERIAL STIFFNESS
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CHILDREN
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EPIDEMIOLOGY
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REFERENCE INTERVALS
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Otras Ciencias Médicas
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Otras Ciencias Médicas
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Reference intervals of aortic pulse wave velocity assessed with an oscillometric device in healthy children and adolescents from Argentina
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-28T18:39:44Z
dc.journal.volume
41
dc.journal.number
2
dc.journal.pagination
101-112
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Díaz, Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
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Fil: Zócalo, Yanina. Universidad de la República; Uruguay
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Fil: Bia, Daniel. Universidad de la República; Uruguay
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Fil: Sabino, Franco. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
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Fil: Rodríguez, Victoria. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
dc.description.fil
Fil: Cabrera Fischer, Edmundo Ignacio. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; Argentina
dc.journal.title
Clinical and Experimental Hypertension
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/10641963.2018.1445754
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/10641963.2018.1445754
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