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dc.contributor.author
Conde, Alvaro José
dc.contributor.author
Battalla, Milena
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Cerda, Maria Belen
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Mykhaylyk, Olga
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Plank, Christian
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Podhajcer, Osvaldo Luis
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Cabaleiro, Juan Martin
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Madrid, Rossana Elena
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Policastro, Lucia Laura
dc.date.available
2016-12-02T20:47:55Z
dc.date.issued
2014-09
dc.identifier.citation
Conde, Alvaro José; Battalla, Milena; Cerda, Maria Belen; Mykhaylyk, Olga; Plank, Christian; et al.; Continuous flow generation of magnetoliposomes in a low-cost portable microfluidic platform; Royal Society Of Chemistry; Lab On A Chip; 14; 23; 9-2014; 4506-4512
dc.identifier.issn
1473-0197
dc.identifier.uri
http://hdl.handle.net/11336/8733
dc.description.abstract
We present a low-cost, portable microfluidic platform that uses laminated polymethylmethacrylate chips, peristaltic micropumps and LEGO® Mindstorms components for the generation of magnetoliposomes that does not require extrusion steps. Mixtures of lipids reconstituted in ethanol and an aqueous phase were injected independently in order to generate a combination of laminar flows in such a way that we could effectively achieve four hydrodynamic focused nanovesicle generation streams. Monodisperse magnetoliposomes with characteristics comparable to those obtained by traditional methods have been obtained. The magnetoliposomes are responsive to external magnetic field gradients, a result that suggests that the nanovesicles can be used in research and applications in nanomedicine.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Royal Society Of Chemistry
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Microfluidics
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Magnetoliposomes
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Nanovesicles
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Methacrylate
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Tecnología de Laboratorios Médicos
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Ingeniería Médica
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INGENIERÍAS Y TECNOLOGÍAS
dc.title
Continuous flow generation of magnetoliposomes in a low-cost portable microfluidic platform
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-11-25T16:34:53Z
dc.journal.volume
14
dc.journal.number
23
dc.journal.pagination
4506-4512
dc.journal.pais
Reino Unido
dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Conde, Alvaro José. Universidad Nacional de Tucuman. Facultad de Cs.exactas y Tecnologia. Departamento de Bioingenieria. Laboratorio de Medios E Interfases; Argentina
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Fil: Battalla, Milena. Comision Nacional de Energia Atomica. Gerencia Quimica. CAC; Argentina
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Fil: Cerda, Maria Belen. Comision Nacional de Energia Atomica. Gerencia Quimica. CAC; Argentina
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Fil: Mykhaylyk, Olga. Technische Universität München. Institute of Experimental Oncology and Therapy Research; Alemania
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Fil: Plank, Christian. Technische Universität München. Institute of Experimental Oncology and Therapy Research; Alemania
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Fil: Podhajcer, Osvaldo Luis. Fundación Instituto Leloir; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina
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Fil: Cabaleiro, Juan Martin. Universidad de Buenos Aires. Facultad de Ingenieria. Departamento de Ingenieria Mecanica. Laboratorio de Fluidodinamica; Argentina
dc.description.fil
Fil: Madrid, Rossana Elena. Universidad Nacional de Tucuman. Facultad de Cs.exactas y Tecnologia. Departamento de Bioingenieria. Laboratorio de Medios E Interfases; Argentina
dc.description.fil
Fil: Policastro, Lucia Laura. Comision Nacional de Energia Atomica. Gerencia Quimica. CAC; Argentina
dc.journal.title
Lab On A Chip
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2014/LC/C4LC00839A#!divAbstract
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/0.1039/c4lc00839a


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