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dc.contributor.author
Tesse, Angela
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Grossini, Elena
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Tamma, Grazia
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Brenner, Catherine
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Portincasa, Piero
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Marinelli, Raul Alberto
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dc.contributor.author
Calamita, Giuseppe
dc.date.available
2019-10-23T21:09:22Z
dc.date.issued
2018-04
dc.identifier.citation
Tesse, Angela; Grossini, Elena; Tamma, Grazia; Brenner, Catherine; Portincasa, Piero; et al.; Aquaporins as targets of dietary bioactive phytocompounds; Frontiers Research Foundation; Frontiers in Molecular Biosciences; 5; APR; 4-2018; 1-13
dc.identifier.issn
2296-889X
dc.identifier.uri
http://hdl.handle.net/11336/87184
dc.description.abstract
Plant-derived bioactive compounds have protective role for plants but may also modulate several physiological processes of plant consumers. In the last years, a wide spectrum of phytochemicals have been found to be beneficial to health interacting with molecular signaling pathways underlying critical functions such as cell growth and differentiation, apoptosis, autophagy, inflammation, redox balance, cell volume regulation, metabolic homeostasis, and energy balance. Hence, a large number of biologically active phytocompounds of foods have been isolated, characterized, and eventually modified representing a natural source of novel molecules to prevent, delay or cure several human diseases. Aquaporins (AQPs), a family of membrane channel proteins involved in many body functions, are emerging among the targets of bioactive phytochemicals in imparting their beneficial actions. Here, we provide a comprehensive review of this fast growing topic focusing especially on what it is known on the modulatory effects played by several edible plant and herbal compounds on AQPs, both in health and disease. Phytochemical modulation of AQP expression may provide new medical treatment options to improve the prognosis of several diseases.
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application/pdf
dc.language.iso
eng
dc.publisher
Frontiers Research Foundation
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ANTI-INFLAMMATORY
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ANTIOXIDANTS
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AQUAPORIN MEMBRANE CHANNELS
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CHRONIC DISEASES
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EPIGENETICS
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FUNCTIONAL FOODS
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GUT MICROBIOTA
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NUTRACEUTICS
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Fisiología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Aquaporins as targets of dietary bioactive phytocompounds
dc.type
info:eu-repo/semantics/article
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info:ar-repo/semantics/artículo
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info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-15T13:19:35Z
dc.journal.volume
5
dc.journal.number
APR
dc.journal.pagination
1-13
dc.journal.pais
Reino Unido
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dc.description.fil
Fil: Tesse, Angela. Universite de Nantes; Francia
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Fil: Grossini, Elena. University East Piedmont; Italia
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Fil: Tamma, Grazia. Università degli Studi di Bari; Italia
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Fil: Brenner, Catherine. Université de Paris XI; Francia
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Fil: Portincasa, Piero. Università degli Studi di Bari; Italia
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Fil: Marinelli, Raul Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Fisiología Experimental. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Fisiología Experimental; Argentina
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Fil: Calamita, Giuseppe. Università degli Studi di Bari; Italia
dc.journal.title
Frontiers in Molecular Biosciences
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fmolb.2018.00030/full
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info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fmolb.2018.00030
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