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dc.contributor.author
Romero Barrios, Natali
dc.contributor.author
Legascue, María Florencia
dc.contributor.author
Benhamed, Moussa
dc.contributor.author
Ariel, Federico Damian
dc.contributor.author
Crespi, Martin
dc.date.available
2019-10-21T18:33:08Z
dc.date.issued
2018-02
dc.identifier.citation
Romero Barrios, Natali; Legascue, María Florencia; Benhamed, Moussa; Ariel, Federico Damian; Crespi, Martin; Splicing regulation by long noncoding RNAs; Oxford University Press; Nucleic Acids Research; 46; 5; 2-2018; 2169-2184
dc.identifier.issn
0305-1048
dc.identifier.uri
http://hdl.handle.net/11336/86689
dc.description.abstract
Massive high-throughput sequencing techniques allowed the identification of thousands of noncoding RNAs (ncRNAs) and a plethora of different mRNA processing events occurring in higher organisms. Long ncRNAs can act directly as long transcripts or can be processed into active small si/miRNAs. They can modulate mRNA cleavage, translational repression or the epigenetic landscape of their target genes. Recently, certain long ncRNAs have been shown to play a crucial role in the regulation of alternative splicing in response to several stimuli or during disease. In this review, we focus on recent discoveries linking gene regulation by alternative splicing and its modulation by long and small ncRNAs.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Oxford University Press
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
splicing regulation
dc.subject
LNCsRNAs
dc.subject
epigenetics
dc.subject
alternative splicing
dc.subject.classification
Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Splicing regulation by long noncoding RNAs
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-10-18T18:37:11Z
dc.identifier.eissn
1362-4962
dc.journal.volume
46
dc.journal.number
5
dc.journal.pagination
2169-2184
dc.journal.pais
Reino Unido
dc.journal.ciudad
Oxford
dc.description.fil
Fil: Romero Barrios, Natali. Universite Paris-sud Xi;
dc.description.fil
Fil: Legascue, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
dc.description.fil
Fil: Benhamed, Moussa. Universite Paris-sud Xi;
dc.description.fil
Fil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina
dc.description.fil
Fil: Crespi, Martin. Universite Paris-sud Xi;
dc.journal.title
Nucleic Acids Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky095/4841659
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1093/nar/gky095
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