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dc.contributor.author
Imperiale, Julieta Celeste
dc.contributor.author
Sosnik, Alejandro Dario
dc.date.available
2019-09-27T17:16:15Z
dc.date.issued
2015-05
dc.identifier.citation
Imperiale, Julieta Celeste; Sosnik, Alejandro Dario; Cyclodextrin complexes for treatment improvement in infectious diseases; Future Medicine; Nanomedicine; 10; 10; 5-2015; 1621-1641
dc.identifier.issn
1743-5889
dc.identifier.uri
http://hdl.handle.net/11336/84671
dc.description.abstract
Infectious diseases are a heterogeneous group of maladies that represent a serious burden to healthcare systems worldwide. Most of the available antimicrobial drugs display poor biopharmaceutical properties that compromise their effectiveness. Cyclodextrins (CDs) are cyclic oligosaccharides of glucopyranose formed by a variable number of repeating units that combine a hydrophilic surface with a hydrophobic cavity. The production of drug/CD complexes has become one of the most extensively investigated technology approaches to improve the stability, solubility, dissolution rate and bioavailability of drugs. The present work overviews the applications of CDs for the formulation of anti-infective agents along with the most relevant administration routes. Finally, an update on the complexes with CDs available on the market to treat infectious diseases is presented.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Future Medicine
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CYCLODEXTRINS
dc.subject
DRUG/CYCLODEXTRIN COMPLEX
dc.subject
INFECTIOUS DISEASES
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LOW PHYSICAL STABILITY
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POOR AQUEOUS SOLUBILITY
dc.subject.classification
Otras Nanotecnología
dc.subject.classification
Nanotecnología
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Cyclodextrin complexes for treatment improvement in infectious diseases
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-09-26T17:09:54Z
dc.journal.volume
10
dc.journal.number
10
dc.journal.pagination
1621-1641
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Imperiale, Julieta Celeste. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Sosnik, Alejandro Dario. Technion - Israel Institute of Technology; Israel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Nanomedicine
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2217/nnm.15.16
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/10.2217/nnm.15.16
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