Artículo
Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm-zona pellucida binding
Marin Briggiler, Clara Isabel
; González Echeverría, María F.; Munuce, María José; Ghersevich, Sergio Albino; Caille, Adriana M.; Hellman, Ulf; Corrigall, Valerie M.; Vazquez, Monica Hebe
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Fecha de publicación:
03/2010
Editorial:
Elsevier Science Inc
Revista:
Fertility and Sterility
ISSN:
0015-0282
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
To determine the secretion of Grp78 by human oviduct epithelial cells, its association to spermatozoa, and its involvement in gamete interaction. Prospective study. Basic research laboratory. Semen samples obtained from normozoospermic volunteers. Tubal tissue provided by patients undergoing hysterectomies. Oocytes collected from women undergoing IVF-ET. Analysis of Grp78 expression and secretion by oviductal tissue. Gamete incubation with recombinant Grp78 (rec-Grp78).
Palabras clave:
BIP
,
CHAPERONE
,
GAMETE INTERACTION
,
GRP78
,
OVIDUCT
,
SPERMATOZOA
,
ZONA PELLUCIDA
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Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Marin Briggiler, Clara Isabel; González Echeverría, María F.; Munuce, María José; Ghersevich, Sergio Albino; Caille, Adriana M.; et al.; Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm-zona pellucida binding; Elsevier Science Inc; Fertility and Sterility; 93; 5; 3-2010; 1574-1584
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