Artículo
Antibacterial properties of water-soluble gold(I) N-heterocyclic carbene complexes
Fernandez, Gabriela Araceli
; Vela Gurovic, Maria Soledad
; Olivera, Nelda Lila
; Chopa, Alicia B.; Silbestri, Gustavo Fabián
Fecha de publicación:
11/03/2014
Editorial:
Elsevier
Revista:
Journal Of Inorganic Biochemistry
ISSN:
0162-0134
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The antibacterial properties of water-soluble gold(I) complexes [1-methyl-3-(3-sulfonatopropyl)imidazol-2- ylidene]gold(I) chloride (C1), [1-mesityl-3-(3-sulfonatopropyl)imidazol-2-ylidene]gold(I) chloride (C2), [1-(2,6- diisopropylphenyl)-3-(3-sulfonatopropyl)imidazol-2-ylidene]gold(I) chloride (C3) and [1,3-bis(2,6-diisopropyl- 4-sodiumsulfonatophenyl)imidazol-2-ylidene]gold(I) chloride (C4) and the respective ligands were assessed by agar diffusion and broth macrodilution methods against Gram-positives Staphylococcus aureus, Enterococcus faecalis and Micrococcus luteus and the Gram-negative bacteria Yersinia ruckeri, Pseudomonas aeruginosa and Escherichia coli. Viability after treatments was determined by direct plate count. The bactericidal activity displayed by C1 and C3 was comparable to that of AgNO3.
Palabras clave:
Water-Soluble Au(I)
,
N-Heterocyclic Carbene
,
Antibacterial
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Colecciones
Articulos(CCT-CENPAT)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CENPAT
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CENPAT
Articulos(INQUISUR)
Articulos de INST.DE QUIMICA DEL SUR
Articulos de INST.DE QUIMICA DEL SUR
Citación
Fernandez, Gabriela Araceli; Vela Gurovic, Maria Soledad; Olivera, Nelda Lila; Chopa, Alicia B.; Silbestri, Gustavo Fabián; Antibacterial properties of water-soluble gold(I) N-heterocyclic carbene complexes; Elsevier; Journal Of Inorganic Biochemistry; 135; 11-3-2014; 54-57
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