Mostrar el registro sencillo del ítem
dc.contributor.author
Arias, Paulina
dc.contributor.author
Ferreyra, Nancy Fabiana
dc.contributor.author
Rivas, Gustavo Adolfo
dc.contributor.author
Bollo, Soledad
dc.date.available
2019-09-04T13:20:45Z
dc.date.issued
2009-09
dc.identifier.citation
Arias, Paulina; Ferreyra, Nancy Fabiana; Rivas, Gustavo Adolfo; Bollo, Soledad; Glassy carbon electrodes modified with CNT dispersed in chitosan: Analytical applications for sensing DNA-methylene blue interaction; Elsevier Science Sa; Journal of Electroanalytical Chemistry; 634; 2; 9-2009; 123-126
dc.identifier.issn
1572-6657
dc.identifier.uri
http://hdl.handle.net/11336/82855
dc.description.abstract
In this work we report the optimization of a chitosan (CHI) and carbon nanotubes (CNT) modified electrode, CNT-CHI, to study the dsDNA interaction with methylene blue (MB), a well-known DNA intercalator. The analytical signal was the reduction current of the MB associated with the dsDNA confined at CNT-CHI modified glassy carbon electrode. The selected CNT-CHI film stabilizing treatment was immersion for 2 s in a 0.20% GTA solution. The effect of ionic strength was also analyzed, concluding that high concentration of NaCl (90 mM) benefits the intercalative process. Below these conditions, a linear response between intensity current and MB concentration was obtained. In conclusion, modifying the initial conditions of the assembling GCE/CHI-CNT/dsDNA electrode the intercalative process was favored opening a fast and cheap possibility to evaluate the toxicity of new synthesized molecules.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science Sa
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Carbon Nanotubes
dc.subject
Chitosan
dc.subject
Dna Damage
dc.subject
Glassy Carbon Electrode
dc.subject
Methylene Blue Electrochemistry
dc.subject
Methylene Blue Sensor
dc.subject.classification
Química Analítica
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Glassy carbon electrodes modified with CNT dispersed in chitosan: Analytical applications for sensing DNA-methylene blue interaction
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-05-06T13:48:23Z
dc.journal.volume
634
dc.journal.number
2
dc.journal.pagination
123-126
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Arias, Paulina. Universidad de Chile; Chile
dc.description.fil
Fil: Ferreyra, Nancy Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
dc.description.fil
Fil: Rivas, Gustavo Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
dc.description.fil
Fil: Bollo, Soledad. Universidad de Chile; Chile
dc.journal.title
Journal of Electroanalytical Chemistry
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0022072809002800
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.jelechem.2009.07.022
Archivos asociados