Artículo
Electrospun scaffolds with enlarged pore size: Porosimetry analysis
Cortez Tornello, Pablo Roberto
; Caracciolo, Pablo Christian
; Igartúa Roselló, Juan I.; Abraham, Gustavo Abel
Fecha de publicación:
09/2018
Editorial:
Elsevier Science
Revista:
Materials Letters
ISSN:
0167-577X
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Electrospun polymeric/composite scaffolds exhibit a micro/nanofibrous structure that resembles the architecture of native extracellular matrix. The unique properties of the interconnected pores and high porosity of electrospun matrices make them very attractive for applications in tissue engineering scaffolding. However, these structures are formed by densely compacted fibers that exhibit pore sizes lower than cell size, leading to poor cell infiltration. In this work, bead-free electrospun poly(ε-caprolactone) fibrous scaffolds were prepared by combining electrospinning and salt-leaching techniques. Non-woven scaffolds were obtained using porogens with different sizes. Liquid extrusion porosimetry was used to accurately determine pore size and its distribution. The structural features of prepared matrices were dependent on the initial porogen size but resulted much smaller than this one.
Palabras clave:
Electrospinning
,
Electrospun Scaffolds
,
Porosimetry
,
Porous Structures
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Articulos(INTEMA)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Citación
Cortez Tornello, Pablo Roberto; Caracciolo, Pablo Christian; Igartúa Roselló, Juan I.; Abraham, Gustavo Abel; Electrospun scaffolds with enlarged pore size: Porosimetry analysis; Elsevier Science; Materials Letters; 227; 9-2018; 191-193
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