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dc.contributor.author
Guercio, Gabriela Viviana  
dc.contributor.author
Constanzo, Mariana  
dc.contributor.author
Grinspon, Romina  
dc.contributor.author
Rey, Rodolfo Alberto  
dc.date.available
2016-11-14T17:38:33Z  
dc.date.issued
2015-09  
dc.identifier.citation
Guercio, Gabriela Viviana; Constanzo, Mariana; Grinspon, Romina; Rey, Rodolfo Alberto; Fertility Issues in Disorders of Sex Development; Elsevier; Endocrinology And Metabolism Clinics Of North America; 44; 4; 9-2015; 867-881  
dc.identifier.issn
0889-8529  
dc.identifier.uri
http://hdl.handle.net/11336/8180  
dc.description.abstract
Fertility potential in patients with disorders of sex development is influenced by specific factors related to the causal disorder, and general functional and anatomic features, irrespective of the etiology. In patients with testicular dysgenesis, severe forms are raised as females, and motherhood might be possible with hormone replacement and oocyte donation. In patients with specific defects of androgen synthesis or action, the absence of uterus and Fallopian tubes hampers motherhood. In some virilized 46,XX patients raised as females, fertility is possible after adequate hormonal and surgical treatments. Patients raised as males are most frequently oligospermic or azoospermic, with the exception for milder forms, where full spermatogenesis can be achieved spontaneously or after hormonal treatment.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Genitales Ambiguos  
dc.subject
Desorden de La Diferenciación Sexual  
dc.subject
Fertilidad  
dc.subject.classification
Endocrinología y Metabolismo  
dc.subject.classification
Medicina Clínica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Fertility Issues in Disorders of Sex Development  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2016-11-11T16:52:14Z  
dc.journal.volume
44  
dc.journal.number
4  
dc.journal.pagination
867-881  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Philadelphia  
dc.description.fil
Fil: Guercio, Gabriela Viviana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina  
dc.description.fil
Fil: Constanzo, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina  
dc.description.fil
Fil: Grinspon, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina  
dc.description.fil
Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina  
dc.journal.title
Endocrinology And Metabolism Clinics Of North America  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0889852915000882  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ecl.2015.07.012