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dc.contributor.author
Guercio, Gabriela Viviana
dc.contributor.author
Constanzo, Mariana
dc.contributor.author
Grinspon, Romina
dc.contributor.author
Rey, Rodolfo Alberto
dc.date.available
2016-11-14T17:38:33Z
dc.date.issued
2015-09
dc.identifier.citation
Guercio, Gabriela Viviana; Constanzo, Mariana; Grinspon, Romina; Rey, Rodolfo Alberto; Fertility Issues in Disorders of Sex Development; Elsevier; Endocrinology And Metabolism Clinics Of North America; 44; 4; 9-2015; 867-881
dc.identifier.issn
0889-8529
dc.identifier.uri
http://hdl.handle.net/11336/8180
dc.description.abstract
Fertility potential in patients with disorders of sex development is influenced by specific factors related to the causal disorder, and general functional and anatomic features, irrespective of the etiology.
In patients with testicular dysgenesis, severe forms are raised as females, and motherhood might be possible with hormone replacement and oocyte donation.
In patients with specific defects of androgen synthesis or action, the absence of uterus and Fallopian tubes hampers motherhood.
In some virilized 46,XX patients raised as females, fertility is possible after adequate hormonal and surgical treatments. Patients raised as males are most frequently oligospermic or azoospermic, with the exception for milder forms, where full spermatogenesis can be achieved spontaneously or after hormonal treatment.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Genitales Ambiguos
dc.subject
Desorden de La Diferenciación Sexual
dc.subject
Fertilidad
dc.subject.classification
Endocrinología y Metabolismo
dc.subject.classification
Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Fertility Issues in Disorders of Sex Development
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-11-11T16:52:14Z
dc.journal.volume
44
dc.journal.number
4
dc.journal.pagination
867-881
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Philadelphia
dc.description.fil
Fil: Guercio, Gabriela Viviana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
dc.description.fil
Fil: Constanzo, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
dc.description.fil
Fil: Grinspon, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina
dc.description.fil
Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
dc.journal.title
Endocrinology And Metabolism Clinics Of North America
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0889852915000882
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ecl.2015.07.012
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