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dc.contributor.author
Christensen, A.
dc.contributor.author
Bentley, G. E.
dc.contributor.author
Cabrera Kreiker, Ricardo Jorge
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dc.contributor.author
Ortega, Hugo Hector
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dc.contributor.author
Perfito, N.
dc.contributor.author
Wu, T. J.
dc.contributor.author
Micevych, P.
dc.date.available
2019-07-26T14:18:13Z
dc.date.issued
2012-06
dc.identifier.citation
Christensen, A.; Bentley, G. E.; Cabrera Kreiker, Ricardo Jorge; Ortega, Hugo Hector; Perfito, N.; et al.; Hormonal regulation of female reproduction; Georg Thieme Verlag Kg; Hormone and Metabolic Research; 44; 8; 6-2012; 587-591
dc.identifier.issn
0018-5043
dc.identifier.uri
http://hdl.handle.net/11336/80365
dc.description.abstract
Reproduction is an event that requires the coordination of peripheral organs with the nervous system to ensure that the internal and external environments are optimal for successful procreation of the species. This is accomplished by the hypothalamic-pituitary-gonadal axis that coordinates reproductive behavior with ovulation. The primary signal from the central nervous system is gonadotropin-releasing hormone (GnRH), which modulates the activity of anterior pituitary gonadotropes regulating follicle stimulating hormone (FSH) and luteinizing hormone (LH) release. As ovarian follicles develop they release estradiol, which negatively regulates further release of GnRH and FSH. As estradiol concentrations peak they trigger the surge release of GnRH, which leads to LH release inducing ovulation. Release of GnRH within the central nervous system helps modulate reproductive behaviors providing a node at which control of reproduction is regulated. To address these issues, this review focuses on several critical questions. How is the HPG axis regulated in species with different reproductive strategies? What internal and external conditions modulate the synthesis and release of GnRH? How does GnRH modulate reproductive behavior within the hypothalamus? How does disease shift the activity of the HPG axis.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Georg Thieme Verlag Kg
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Estradiol
dc.subject
Gnrh
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Hpg Axis
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Lh Surge
dc.subject.classification
Medicina Critica y de Emergencia
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dc.subject.classification
Medicina Clínica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Hormonal regulation of female reproduction
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-06-10T21:20:58Z
dc.journal.volume
44
dc.journal.number
8
dc.journal.pagination
587-591
dc.journal.pais
Alemania
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dc.description.fil
Fil: Christensen, A.. University of California at Los Angeles; Estados Unidos
dc.description.fil
Fil: Bentley, G. E.. University of California at Berkeley; Estados Unidos
dc.description.fil
Fil: Cabrera Kreiker, Ricardo Jorge. Universidad de Mendoza; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina
dc.description.fil
Fil: Ortega, Hugo Hector. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Litoral; Argentina
dc.description.fil
Fil: Perfito, N.. University of California at Berkeley; Estados Unidos
dc.description.fil
Fil: Wu, T. J.. Uniformed Services University Of The Health Sciences; Estados Unidos
dc.description.fil
Fil: Micevych, P.. University of California at Los Angeles; Estados Unidos
dc.journal.title
Hormone and Metabolic Research
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1055/s-0032-1306301
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647363/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0032-1306301
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