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dc.contributor.author
Picado, Albert  
dc.contributor.author
Cruz, Israel  
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Redard Jacot, Maël  
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Schijman, Alejandro Gabriel  
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Torrico, Faustino  
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Sosa-Estani, Sergio Alejandro  
dc.contributor.author
Katz, Zachary  
dc.contributor.author
Ndung'u, Joseph Mathu  
dc.date.available
2019-07-18T20:57:25Z  
dc.date.issued
2018-10  
dc.identifier.citation
Picado, Albert; Cruz, Israel; Redard Jacot, Maël; Schijman, Alejandro Gabriel; Torrico, Faustino; et al.; The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America; BMJ Publishing Group; BMJ Global Health; 3; 5; 10-2018; 1-7  
dc.identifier.issn
2059-7908  
dc.identifier.uri
http://hdl.handle.net/11336/79859  
dc.description.abstract
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy at birth and serology at 8-12 months after delivery, is one of the barriers to congenital Chagas disease (CCD) control. Detection of parasite DNA using molecular diagnostic tools could be an alternative or complement to current diagnostic methods, but its implementation in endemic regions remains limited. Prompt diagnosis and treatment of CCD cases would have a positive clinical and epidemiological impact. In this paper, we analysed the burden of CCD in Latin America, and the potential use of molecular tests to improve access to early diagnosis and treatment of T. cruzi infected newborns.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
BMJ Publishing Group  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Lamp  
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Molecular Tools  
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Trypanosoma Cruzi  
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Chagas Disease  
dc.subject.classification
Enfermedades Infecciosas  
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Ciencias de la Salud  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2019-07-17T14:41:56Z  
dc.identifier.eissn
0959-535X  
dc.journal.volume
3  
dc.journal.number
5  
dc.journal.pagination
1-7  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Picado, Albert. Foundation for Innovative New Diagnostics; Suiza  
dc.description.fil
Fil: Cruz, Israel. Foundation for Innovative New Diagnostics; Suiza  
dc.description.fil
Fil: Redard Jacot, Maël. Foundation for Innovative New Diagnostics; Suiza  
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Fil: Schijman, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina  
dc.description.fil
Fil: Torrico, Faustino. Universidad Mayor de San Simón; Bolivia. Fundación CEADES; Bolivia  
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Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Drugs for Neglected Diseases initiative; Brasil  
dc.description.fil
Fil: Katz, Zachary. Foundation for Innovative New Diagnostics; Suiza  
dc.description.fil
Fil: Ndung'u, Joseph Mathu. Foundation for Innovative New Diagnostics; Suiza  
dc.journal.title
BMJ Global Health  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://gh.bmj.com/content/3/5/e001069  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1136/bmjgh-2018-001069