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dc.contributor.author
Langguth, Berthold  
dc.contributor.author
Elgoyhen, Ana Belen  
dc.date.available
2019-07-11T17:32:56Z  
dc.date.issued
2012-12  
dc.identifier.citation
Langguth, Berthold; Elgoyhen, Ana Belen; Current pharmacological treatments for tinnitus; Taylor & Francis; Expert Opinion on Pharmacotherapy; 13; 17; 12-2012; 2495-2509  
dc.identifier.issn
1465-6566  
dc.identifier.uri
http://hdl.handle.net/11336/79355  
dc.description.abstract
Introduction: Tinnitus, the phantom perception of sound, is a highly prevalent disorder and treatment is elusive. Areas covered: This review focuses on clinical research regarding pharmacological treatments for tinnitus. The authors searched PubMed databases for English language articles related to pharmacological treatment of tinnitus, published through August 2012. The keywords tinnitus AND pharmacological treatment" and "tinnitus AND drugs" were used. The search focused on clinical trials, but was complemented by other articles and information from clinical trial registries. Expert opinion: Despite the significant unmet clinical need for a safe and effective drug for tinnitus relief, there is currently no EMA- or FDA-approved drug on the market. Even a drug that produces a small but significant effect would have a huge therapeutic impact. At present, evidence-based pharmacological approaches are limited to the treatment of comorbidities such as depression, anxiety, or insomnia. In the last few years there have been significant advances in the understanding of the pathophysiology of the different forms of tinnitus, the establishment of valid animal models, and the development of clinical trial methodology. A glimpse of hope is appearing in the horizon as an increasing number of pharmaceutical industries now have compounds targeting tinnitus in their pipeline.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Taylor & Francis  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Auditory System  
dc.subject
Hearing  
dc.subject
Meta-Analysis  
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Pharmacotherapy  
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Randomized Controlled Trial  
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Systematic Review  
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Tinnitus  
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Treatment  
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Medicina Critica y de Emergencia  
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Medicina Clínica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Current pharmacological treatments for tinnitus  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2019-07-10T13:40:05Z  
dc.journal.volume
13  
dc.journal.number
17  
dc.journal.pagination
2495-2509  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Langguth, Berthold. Universitat Regensburg; Alemania  
dc.description.fil
Fil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina  
dc.journal.title
Expert Opinion on Pharmacotherapy  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1517/14656566.2012.739608  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1517/14656566.2012.739608