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dc.contributor.author
Torres, Sebastián  
dc.contributor.author
Pandey, Ashok  
dc.contributor.author
Castro, Guillermo Raul  
dc.date.available
2019-06-05T16:31:57Z  
dc.date.issued
2011-01  
dc.identifier.citation
Torres, Sebastián; Pandey, Ashok; Castro, Guillermo Raul; Organic solvent adaptation of Gram positive bacteria: applications and biotechnological potentials; Pergamon-Elsevier Science Ltd; Biotechnology Advances; 29; 4; 1-2011; 442-452  
dc.identifier.issn
0734-9750  
dc.identifier.uri
http://hdl.handle.net/11336/77639  
dc.description.abstract
Organic-solvent-tolerant bacteria are considered extremophiles with different tolerance levels that change among species and strains, but also depend on the inherent toxicity of the solvent. Extensive studies to understand the mechanisms of organic solvent tolerance have been done in Gram-negative bacteria. On the contrary, the information on the solvent tolerance mechanisms in Gram-positive bacteria remains scarce. Possible shared mechanisms among Gram-(−) and Gram-(+) microorganisms include: energy-dependent active efflux pumps that export toxic organic solvents to the external medium; cis-to-trans isomerization of unsaturated membrane fatty acids and modifications in the membrane phospholipid headgroups; formation of vesicles loaded with toxic compounds; and changes in the biosynthesis rate of phospholipids to accelerate repair processes. However, additional physiological responses of Gram-(+) bacteria to organic solvents seem to be specific. The aim of the present work is to review the state of the art of responsible mechanisms for organic solvent tolerance in Gram-positive bacteria, and their industrial and environmental biotechnology potential.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Pergamon-Elsevier Science Ltd  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Solvent-Tolerance  
dc.subject
Biocatalysis  
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Whole-Cell Biocatalysis  
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Solvent Stress  
dc.subject.classification
Biotecnología Industrial  
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Biotecnología Industrial  
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INGENIERÍAS Y TECNOLOGÍAS  
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Biotecnología Industrial  
dc.subject.classification
Biotecnología Industrial  
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INGENIERÍAS Y TECNOLOGÍAS  
dc.title
Organic solvent adaptation of Gram positive bacteria: applications and biotechnological potentials  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2019-06-04T15:58:01Z  
dc.journal.volume
29  
dc.journal.number
4  
dc.journal.pagination
442-452  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
New York  
dc.description.fil
Fil: Torres, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina  
dc.description.fil
Fil: Pandey, Ashok. Regional Research Laboratory; India  
dc.description.fil
Fil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; Argentina  
dc.journal.title
Biotechnology Advances  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.biotechadv.2011.04.002  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0734975011000413?via%3Dihub