Artículo
Aripiprazole salts. III. Bis(aripiprazolium) oxalate-oxalic acid (1/1)
Fecha de publicación:
02/2013
Editorial:
Wiley Blackwell Publishing, Inc
Revista:
Acta Crystallographica Section C-Crystal Structure Communications
ISSN:
0108-2701
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The asymmetric unit of the title salt [systematic name: bis(4-(2,3-dichlorophenyl)-1-{4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy] butyl}piperazin-1-ium) oxalate-oxalic acid (1/1)], 2C23H28Cl2N3O2 +·C2O4 2-·C2H2O4, consists of one protonated aripiprazole unit (HArip+), half an oxalate dianion and half an oxalic acid molecule, the latter two lying on inversion centres. The conformation of the HArip+ cation differs from that in other reported salts and resembles more the conformation of neutral Arip units in reported polymorphs and solvates. The intermolecular interaction linking HArip + cations is also similar to those in reported Arip compounds crystallizing in the space group P , with head-to-head N - H ⋯O hydrogen bonds generating centrosymmetric dimers, which are further organized into planar ribbons parallel to (01 ). The oxalate anions and oxalic acid molecules form hydrogen-bonded chains running along [010], which 'pierce' the planar ribbons, interacting with them through a number of stronger N - H ⋯O and weaker C - H ⋯O hydrogen bonds, forming a three-dimensional network.
Palabras clave:
Aripiprazol
,
Salts
,
Oxalate
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Freire Espeleta, Eleonora; Polla, Griselda Ines; Baggio, Ricardo Fortunato; Aripiprazole salts. III. Bis(aripiprazolium) oxalate-oxalic acid (1/1); Wiley Blackwell Publishing, Inc; Acta Crystallographica Section C-Crystal Structure Communications; 69; 2; 2-2013; 186-190
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