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dc.contributor.author
Correale, Jorge
dc.contributor.author
Farez, Mauricio Franco
dc.contributor.author
Gaitán, María Inés
dc.date.available
2019-05-13T20:43:45Z
dc.date.issued
2017-06
dc.identifier.citation
Correale, Jorge; Farez, Mauricio Franco; Gaitán, María Inés; Environmental factors influencing multiple sclerosis in Latin America; Sage Publications Ltd; Multiple sclerosis journal - experimental, translational and clinical; 3; 2; 6-2017; 1-13
dc.identifier.issn
2055-2173
dc.identifier.uri
http://hdl.handle.net/11336/76213
dc.description.abstract
It is generally accepted that autoimmune diseases like multiple sclerosis (MS) arise from complex interactions between genetic susceptibility and environmental factors. Genetic variants confer predis- position to develop MS, but cannot be therapeutically modified. On the other hand, several studies have shown that different lifestyle and environmental factors influence disease development, as well as activity levels and progression. Unlike genetic risk factors, these can be modified, with potential for prevention, particularly in high-risk populations. Most studies identifying particular lifestyle and environmental factors have been carried out in Caucasian patients with MS. Little or no data is available on the behavior of these factors in Latin American populations. Ethnic and geographic differences between Latin America and other world regions suggest potential regional variations in MS, at least with respect to some of these factors. Furthermore, particular environmental characteristics observed more frequently in Latin America could explain regional differences in MS prevalence. Site-specific studies exploring influences of local environmental factors are warranted.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Sage Publications Ltd
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Environmental Factors
dc.subject
Multiple Sclerosis
dc.subject.classification
Inmunología
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Environmental factors influencing multiple sclerosis in Latin America
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-05-13T18:21:38Z
dc.journal.volume
3
dc.journal.number
2
dc.journal.pagination
1-13
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Thousand Oaks
dc.description.fil
Fil: Correale, Jorge. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
dc.description.fil
Fil: Farez, Mauricio Franco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
dc.description.fil
Fil: Gaitán, María Inés. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
dc.journal.title
Multiple sclerosis journal - experimental, translational and clinical
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1177/2055217317715049
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1177/2055217317715049
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