Artículo
Crosslinked polymer nanoparticles containing single conjugated polymer chains
Ponzio, Rodrigo Andrés
; Marcato, Yesica L.; Gomez, María Lorena
; Waiman, Carolina Vanesa
; Chesta, Carlos Alberto
; Palacios, Rodrigo Emiliano
Fecha de publicación:
06/2017
Editorial:
IOP Publishing Ltd
Revista:
Methods and Applications in Fluorescence
ISSN:
2050-6120
e-ISSN:
2050-6120
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Conjugated polymer nanoparticles are widely used in fluorescent labeling and sensing, as they have mean radii between 5 and 100 nm, narrow size dispersion, high brightness, and are photochemically stable, allowing single particle detection with high spatial and temporal resolution. Highly crosslinked polymers formed by linking individual chains through covalent bonds yield high-strength rigid materials capable of withstanding dissolution by organic solvents. Hence, the combination of crosslinked polymers and conjugated polymers in a nanoparticulated material presents the possibility of interesting applications that require the combined properties of constituent polymers and nanosized dimension. In the present work, F8BT@pEGDMA nanoparticles composed of poly (ethylene glycol dimethacrylate)(pEGDMA; a crosslinked polymer) and containing the commercial conjugated polymer poly(9,9-dioctylfluorene-alt-benzothiadiazole)(F8BT) were synthesized and characterized. Microemulsion polymerization was applied to produce F8BT@pEDGMA particles with nanosized dimensions in a ∼25% yield. Photophysical and size distribution properties of F8BT@pEDGMA nanoparticles were evaluated by various methods, in particular single particle fluorescence microscopy techniques. The results demonstrate that the crosslinking/polymerization process imparts structural rigidity to the F8BT@pEDGMA particles by providing resistance against dissolution/disintegration in organic solvents. The synthesized fluorescent crosslinked nanoparticles contain (for the most part) single F8BT chains and can be detected at the single particle level, using fluorescence microscopy, which bodes well for their potential application as molecularly imprinted polymer fluorescent nanosensors with high spatial and temporal resolution.
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Articulos(CCT - CORDOBA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Articulos(INQUISUR)
Articulos de INST.DE QUIMICA DEL SUR
Articulos de INST.DE QUIMICA DEL SUR
Citación
Ponzio, Rodrigo Andrés; Marcato, Yesica L.; Gomez, María Lorena; Waiman, Carolina Vanesa; Chesta, Carlos Alberto; et al.; Crosslinked polymer nanoparticles containing single conjugated polymer chains; IOP Publishing Ltd; Methods and Applications in Fluorescence; 5; 2; 6-2017; 24001-24001
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