Artículo
Photophysical, photochemical and photobiological properties of anthraquinones isolated from a phototoxic vegetal species: Heterophyllaea pustulata
Fecha de publicación:
02/2010
Editorial:
Research Trends
Revista:
Trends in photochemistry and Photobiology
ISSN:
0972-4532
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Studies undertaken on isolated photosensitizing agents from Heterophyllaea pustulata, a photo-toxic plant, which natural habitat is the North-western part of Argentina, are presented here. The carried out work involved several steps that were initiated with the chemical-structural study of their most important secondary metabolites. As a result, three flavonoids, one iridoid glycoside (asperuloside) and ten aglycone anthraquinones were identified. Through the study of the photo-physical, photochemical and photobiological properties of the anthraquinone derivatives, we concluded that they show good photosensitizing (type I and type II) characteristics. The performed toxicological assays in vivo showed a direct cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Palabras clave:
Photosensitizers
,
Reactive Oxygen Species
,
Anthraquinones
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(IMBIV)
Articulos de INST.MULTIDISCIPL.DE BIOLOGIA VEGETAL (P)
Articulos de INST.MULTIDISCIPL.DE BIOLOGIA VEGETAL (P)
Articulos(INFIQC)
Articulos de INST.DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Articulos de INST.DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Citación
Comini, Laura Raquel; Núñez Montoya, Susana Carolina; Argüello, Gustavo A.; Cabrera, Jose Luis; Photophysical, photochemical and photobiological properties of anthraquinones isolated from a phototoxic vegetal species: Heterophyllaea pustulata; Research Trends; Trends in photochemistry and Photobiology; 12; 2-2010; 17-36
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