Artículo
Angiogenesis at Different Stage of Pregnancy in Goat Placenta
Díaz, Tomás
; Merkis, Cecilia Inés; Cots, Debora Soledad
; Sanchis, Eva Gabriela
; Cristofolini, Andrea Lorena
; Romanini, María Cristina; Bozzo, A.; Rolando, Alicia Nelida
Fecha de publicación:
09/2015
Editorial:
Royal Netherlands Soc Agr Sci
Revista:
Njas - Wageningen Journal of Life Sciences
ISSN:
1573-5214
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The increase intransplacental exchange depends primarily on the great development of the placental vascular bed. The aim of this study was to evaluate the pattern of placental vascular development at day 50 and 100 of pregnancyin goats and the relationship with the vascular endothelial growth factor (VEGF) immunolocalization. The placental morphometric variables:capillary area density, capillary perimeter density, capillary number density and average capillary perimeter of the caruncular (CAR)and cotyledonary (COT) tissues were measured at day 50 (n = 5) and 100 (n = 5) of gestation. Also, the immunolocalization ofVEGF was performed. In the CAR and COT tissues a significant increase of capillary area density and capillary perimeter density at day 100 of the gestation was observed. In the COT tissue, this was due to the increase in the capillary number density; however in the CAR tissue this was due to the increase in the capillary size. We can conclude that in both tissues there were different strategies to increase the capillary area and, thereby, the nutrients exchange. The immunolocalization of VEGF in the COT tissue showed the endothelial cells of blood vessels and trophoblastcells surrounding the villi intensely inmunostained, which would indicate the involvement of VEGF in the placental vascular development.
Palabras clave:
Angiogenesis
,
Placenta
,
Goat
,
Vegf
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - CORDOBA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Citación
Díaz, Tomás; Merkis, Cecilia Inés; Cots, Debora Soledad; Sanchis, Eva Gabriela; Cristofolini, Andrea Lorena; et al.; Angiogenesis at Different Stage of Pregnancy in Goat Placenta; Royal Netherlands Soc Agr Sci; Njas - Wageningen Journal of Life Sciences; 9; 9-2015; 391-398
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