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dc.contributor.author
Ba, Haojin
dc.contributor.author
Rodríguez Fernández, Jessica
dc.contributor.author
Stefani, Fernando Daniel
dc.contributor.author
Feldmann, Jochen
dc.date.available
2019-01-29T20:40:40Z
dc.date.issued
2010-08
dc.identifier.citation
Ba, Haojin; Rodríguez Fernández, Jessica; Stefani, Fernando Daniel; Feldmann, Jochen; Immobilization of gold nanoparticles on living cell membranes upon controlled lipid binding; American Chemical Society; Nano Letters; 10; 8; 8-2010; 3006-3012
dc.identifier.issn
1530-6984
dc.identifier.uri
http://hdl.handle.net/11336/68928
dc.description.abstract
We present a versatile and controlled route to immobilize gold nanoparticles (NPs) on the surface of living cells, while preserving the sensing and optothermal capabilities of the original colloid. Our approach is based on the controlled and selective binding of Au NPs to phospholipids prior to cell incubation. We show that in the presence of the cells the lipid-bound Au NPs are delivered to the cellular membrane and that their diffusion is rather slow and spatially limited, as a result of lipid binding. Avoiding nonspecific membrane labeling, this approach is of general application to several types of colloids and cells and thereby provides a platform for controlled plasmonic and optothermal investigations of living cell membranes.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
American Chemical Society
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Cell Membrane
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Diffusion
dc.subject
Gold Nanoparticles
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Labeling
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Lipid Binding
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Surface Modification
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Otras Ciencias Químicas
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Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Immobilization of gold nanoparticles on living cell membranes upon controlled lipid binding
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2019-01-29T18:08:14Z
dc.journal.volume
10
dc.journal.number
8
dc.journal.pagination
3006-3012
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Ba, Haojin. Ludwig Maximilians Universitat; Alemania
dc.description.fil
Fil: Rodríguez Fernández, Jessica. Ludwig Maximilians Universitat; Alemania
dc.description.fil
Fil: Stefani, Fernando Daniel. Ludwig Maximilians Universitat; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina
dc.description.fil
Fil: Feldmann, Jochen. Ludwig Maximilians Universitat; Alemania
dc.journal.title
Nano Letters
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/nl101454a
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/abs/10.1021/nl101454a
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