Artículo
A Novel Bone Scaffolds Based on Hyperbranched Polyglycerol Fibers Filled with Hydroxyapatite Nanoparticles: In Vitro Cell Response
Alencar de Queiroz, Alvaro Antonio; Bressiani, José Carlos; Bressiani, Ana Helena A.; Higa, Olga Z.; Abraham, Gustavo Abel
Fecha de publicación:
10/2008
Editorial:
Trans Tech Publications
Revista:
Key Engineering Materials
ISSN:
1662-9795
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A novel bone scaffolding material was successfully fabricated by electrospinning from hyperbranched polyglycerol (HPGL) solutions containing nanoparticles of hydroxyapatite (HA). The potential use of the electrospun fibrous HPGL-HA scaffolds for bone regeneration was evaluated in vitro with human osteoblasts in terms of alkaline phosphatase (ALP) activity of the cells that were cultured directly on the scaffolds. The results were compared with those on corresponding HPLG-HA solution-cast film scaffolds. It was found that all of the fibrous scaffolds promoted much better adhesion and proliferation of cells than the corresponding film scaffolds.
Palabras clave:
Scaffolds
,
Nanocomposites
,
Electrospinning
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Tamaño:
398.1Kb
Formato:
PDF
Licencia
Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción:
Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
Colecciones
Articulos(INTEMA)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Citación
Alencar de Queiroz, Alvaro Antonio; Bressiani, José Carlos; Bressiani, Ana Helena A.; Higa, Olga Z.; Abraham, Gustavo Abel; A Novel Bone Scaffolds Based on Hyperbranched Polyglycerol Fibers Filled with Hydroxyapatite Nanoparticles: In Vitro Cell Response; Trans Tech Publications; Key Engineering Materials; 396-398; 10-2008; 633-636
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