Artículo

Novel synthesis of 2-thienylcarbonyl-cyclohexane-1,3-dione as building block for indazolones and isoxazolones

Chans, Guillermo ManuelIcon ; Moyano, Elizabeth LauraIcon ; Yranzo, Gloria InésIcon
Fecha de publicación: 30/05/2011
Editorial: Csiro Publishing
Revista: Australian Journal of Chemistry
ISSN: 0004-9425
e-ISSN: 1445-0038
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

A new synthetic methodology using ultrasonic treatment was applied to the C-acylation of 1,3-cyclohexanedione with thiophene-2-carbonyl chloride to afford 3-hydroxy-2-(2-thienylcarbonyl)cyclohex-2-en-1-one (5). This compound was used as a building block to prepare different bicyclic systems: tetrahydro-4H- indazol-4-ones (7ac and 9a,b,d), and 6,7-dihydrobenzisoxazole (11) by reaction with different hydrazines and hydroxylamine, respectively. Structural elucidation of all compounds was thoroughly achieved by NMR spectroscopy. © CSIRO 2011.
Palabras clave: Acylcyclohexanodiones , Ultrasound , Indazoles , Benzisoxazoles
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/66811
DOI: https://dx.doi.org/10.1071/CH11015
URL: http://www.publish.csiro.au/ch/CH11015
Colecciones
Articulos(INFIQC)
Articulos de INST.DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Citación
Chans, Guillermo Manuel; Moyano, Elizabeth Laura; Yranzo, Gloria Inés; Novel synthesis of 2-thienylcarbonyl-cyclohexane-1,3-dione as building block for indazolones and isoxazolones; Csiro Publishing; Australian Journal of Chemistry; 64; 5; 30-5-2011; 638-646
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