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dc.contributor.author
Garcia, Cybele
dc.contributor.author
Sepúlveda, Claudia Soledad
dc.contributor.author
Damonte, Elsa Beatriz
dc.date.available
2018-12-19T17:38:55Z
dc.date.issued
2011-01
dc.identifier.citation
Garcia, Cybele; Sepúlveda, Claudia Soledad; Damonte, Elsa Beatriz; Novel therapeutic targets for arenavirus hemorrhagic fevers; Future Medicine; Future Virology; 6; 1; 1-2011; 27-44
dc.identifier.issn
1746-0794
dc.identifier.uri
http://hdl.handle.net/11336/66763
dc.description.abstract
Several members of the family Arenaviridae can cause severe hemorrhagic fevers in humans, representing a serious public health problem in endemic areas of Africa and South America. The Lassa virus is the most prevalent and dangerous arenavirus, causing over 300,000 infections per year and several thousand deaths. Furthermore, pathogenic arenaviruses are considered as category A potential agents for bioterrorism. Based on the danger of arenaviruses for human health, the increased emergence of new viral species in recent years and the lack of effective tools for their control or prevention, the search for novel antiviral compounds effective against these pathogenic agents is a continuous demanding effort. This article focuses on novel strategies to identify inhibitors for arenavirus therapy, analyzing viral and host proteins essential for virus infection as potential targets for antiviral development. © 2011 Future Medicine Ltd.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Future Medicine
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Antiviral Agent
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Arenavirus
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Junin Virus
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Lassa Virus
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Therapeutic Target
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Viral Hemorrhagic Fevers
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Otras Ciencias Biológicas
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Novel therapeutic targets for arenavirus hemorrhagic fevers
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-11-22T15:28:10Z
dc.journal.volume
6
dc.journal.number
1
dc.journal.pagination
27-44
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Garcia, Cybele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
dc.description.fil
Fil: Sepúlveda, Claudia Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
dc.description.fil
Fil: Damonte, Elsa Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
dc.journal.title
Future Virology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/10.2217/fvl.10.65
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.2217/fvl.10.65
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