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dc.contributor.author García, Adolfo Martín
dc.contributor.author Sedeño, Lucas
dc.contributor.author Herrera Murcia, Eduar
dc.contributor.author Couto, Juan Blas Marcos
dc.contributor.author Ibáñez Barassi, Agustín Mariano
dc.date.available 2018-12-18T17:57:21Z
dc.date.issued 2017-01
dc.identifier.citation García, Adolfo Martín; Sedeño, Lucas; Herrera Murcia, Eduar; Couto, Juan Blas Marcos; Ibáñez Barassi, Agustín Mariano; A lesion-proof brain? Multidimensional sensorimotor, cognitive, and socio-affective preservation despite extensive damage in a stroke patient; Frontiers Media S.A.; Frontiers in Aging Neuroscience; 8; JAN; 1-2017; 1-10
dc.identifier.issn 1663-4365
dc.identifier.uri http://hdl.handle.net/11336/66670
dc.description.abstract In this study, we report an unusual case of mutidimensional sensorimotor, cognitive, and socio-affective preservation in an adult with extensive, acquired bilateral brain damage. At age 43, patient CG sustained a cerebral hemorrhage and a few months later, she suffered a second (ischemic) stroke. As a result, she exhibited extensive damage of the right hemisphere (including frontal, temporal, parietal, and occipital regions), left Sylvian and striatal areas, bilateral portions of the insula and the amygdala, and the splenium. However, against all probability, she was unimpaired across a host of cognitive domains, including executive functions, attention, memory, language, sensory perception (e.g., taste recognition and intensity discrimination), emotional processing (e.g., experiencing of positive and negative emotions), and social cognition skills (prosody recognition, theory of mind, facial emotion recognition, and emotional evaluation). Her functional integrity was further confirmed through neurological examination and contextualized observation of her performance in real-life tasks. In sum, CG's case resists straightforward classifications, as the extent and distribution of her lesions would typically produce pervasive, multidimensional deficits. We discuss the rarity of this patient against the backdrop of other reports of atypical cognitive preservation, expound the limitations of several potential accounts, and highlight the challenges that the case poses for current theories of brain organization and resilience.
dc.format application/pdf
dc.language.iso eng
dc.publisher Frontiers Media S.A.
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject BILATERAL LESIONS
dc.subject COGNITIVE RESERVE
dc.subject MULTIMODAL PRESERVATION
dc.subject STROKE
dc.subject.classification Inmunología
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title A lesion-proof brain? Multidimensional sensorimotor, cognitive, and socio-affective preservation despite extensive damage in a stroke patient
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2018-11-02T17:31:03Z
dc.journal.volume 8
dc.journal.number JAN
dc.journal.pagination 1-10
dc.journal.pais Suiza
dc.journal.ciudad Lausanne
dc.description.fil Fil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva; Argentina. Universidad Nacional de Cuyo; Argentina
dc.description.fil Fil: Sedeño, Lucas. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva; Argentina
dc.description.fil Fil: Herrera Murcia, Eduar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Icesi; Colombia
dc.description.fil Fil: Couto, Juan Blas Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva; Argentina
dc.description.fil Fil: Ibáñez Barassi, Agustín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva; Argentina. Universidad Autónoma del Caribe; Colombia. Universidad Adolfo Ibañez; Chile. Australian Research Council; Australia
dc.journal.title Frontiers in Aging Neuroscience
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.3389/fnagi.2016.00335
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnagi.2016.00335
dc.conicet.fuente unificacion


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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)