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dc.contributor.author
Gambaro, Sabrina Eliana
dc.contributor.author
Romero, P.
dc.contributor.author
Pedraza, N.
dc.contributor.author
Moulin, L.
dc.contributor.author
Yantorno, S.
dc.contributor.author
Ramisch, D.
dc.contributor.author
Rumbo, Carolina
dc.contributor.author
Barros Schelotto, Pablo
dc.contributor.author
Descalzi, Ricardo Luis
dc.contributor.author
Gondolesi, Gabriel Eduardo
dc.date.available
2018-12-18T13:07:43Z
dc.date.issued
2017-11
dc.identifier.citation
Gambaro, Sabrina Eliana; Romero, P.; Pedraza, N.; Moulin, L.; Yantorno, S.; et al.; Right Extended Split Liver Transplantation Compared With Whole Liver Transplantation: Lessons Learned at a Single Center in Latin America—Results From a Match Case-Control Study; Elsevier Science Inc; Transplantation Proceedings; 49; 9; 11-2017; 2122-2128
dc.identifier.issn
0041-1345
dc.identifier.uri
http://hdl.handle.net/11336/66638
dc.description.abstract
Background Despite the progressively increasing gap between patients waiting for liver transplant under the Model for End-stage Liver Disease MELD system and the availability of deceased donor organs, the use of right extended split liver grafts (RESLG) has not been accepted by all centers. In this study, we compared the results obtained using RESLG vs a group of matched whole liver graft (WLG) recipients at a single center in Latin America. Methods A single-center retrospective review performed between August 2009 and December 2015. Results Fifteen RESLGs were implanted to recipients between 13 and 70 years of age; 80% were performed ex situ. The “biological MELD” score for the RESLG group was 17.5 ± 5.6, and it was 12.8 ± 4.5 for the WLG group (P =.01). Cold ischemia times were significantly longer in RESLG recipients compared with WLG recipients (528 minutes vs 420 minutes; P <.01). No significant differences were found in biliary (leak or strictures P =.40) and arterial complications (hepatic artery thrombosis, P =.06). RESLG patients benefited from a considerable reduction on their waiting time in list. The 1-, 3-, and 5-year patient survival rates were 93%, 93%, and 93% respectively, for RESLG recipients vs 100%, 95.7%, and 86.1%, respectively, for WLG recipients. The 1-, 3-, and 5-year graft survival rates were 79.4%, 79.4%, and 79.4% for RESLG recipients and 89.7%, 89.7%, and 89.7% for WLG recipients, respectively. No statistical differences were observed. Conclusion RESLG allows expeditious transplantation for low MELD recipients. Its use should be expanded in Latin America and worldwide as a valid alternative to increase the donor pool as it has been used in other regions.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Right Extended Split Liver Transplantation
dc.subject
Transplantation Outcomes
dc.subject
Donor Selection
dc.subject
Biliary Complications
dc.subject.classification
Medicina Critica y de Emergencia
dc.subject.classification
Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Right Extended Split Liver Transplantation Compared With Whole Liver Transplantation: Lessons Learned at a Single Center in Latin America—Results From a Match Case-Control Study
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-22T21:50:56Z
dc.journal.volume
49
dc.journal.number
9
dc.journal.pagination
2122-2128
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Nueva York
dc.description.fil
Fil: Gambaro, Sabrina Eliana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Favaloro; Argentina
dc.description.fil
Fil: Romero, P.. Fundación Favaloro; Argentina
dc.description.fil
Fil: Pedraza, N.. Fundación Favaloro; Argentina
dc.description.fil
Fil: Moulin, L.. Fundación Favaloro; Argentina
dc.description.fil
Fil: Yantorno, S.. Fundación Favaloro; Argentina
dc.description.fil
Fil: Ramisch, D.. Fundación Favaloro; Argentina
dc.description.fil
Fil: Rumbo, Carolina. Fundación Favaloro; Argentina
dc.description.fil
Fil: Barros Schelotto, Pablo. Fundación Favaloro; Argentina
dc.description.fil
Fil: Descalzi, Ricardo Luis. Fundación Favaloro; Argentina
dc.description.fil
Fil: Gondolesi, Gabriel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Fundación Favaloro; Argentina
dc.journal.title
Transplantation Proceedings
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.transproceed.2017.07.019
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0041134517307108
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