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dc.contributor.author
Casais, Patricia
dc.contributor.author
Meschengieser, Carolina
dc.contributor.author
Sánchez Luceros, Analía Gabriela
dc.contributor.author
Lazzari, María Ángela
dc.date.available
2018-12-17T18:53:33Z
dc.date.issued
2005-07
dc.identifier.citation
Casais, Patricia; Meschengieser, Carolina; Sánchez Luceros, Analía Gabriela; Lazzari, María Ángela; Patients' perceptions regarding oral anticoagulation therapy and its effect on quality of life; Librapharm/informa Healthcare; Current Medical Research And Opinion.; 21; 7; 7-2005; 1085-1090
dc.identifier.issn
0300-7995
dc.identifier.uri
http://hdl.handle.net/11336/66590
dc.description.abstract
Objective: Anticoagulation clinics have improved the time spent within therapeutic range and decreased hemorrhagic complications and costs in chronic oral anticoagulation. Whether these benefits correlate to patients' quality of life (QOL) remains to be determined. The impact of patients' perceptions about anticoagulation on QOL has not been evaluated. The objective of this study was to evaluate prospectively patients' perceptions and quality of life in patients chronically anticoagulated. Research design and methods: A cross-sectional study was designed to investigate the prevalence of positive and negative perceptions about oral anticoagulation therapy (OAT) and to identify vulnerable groups. Patients anonymously completed the SF-36 survey and a questionnaire that focused on patients' perceptions of protection from thrombotic complications or fear of haemorrhage due to the anticoagulation. We related those perceptions to the General Health SF-36 score, to the patient's characteristics, the absolute bleeding risk (i.e. intended International Normalized Ratio [INR]), duration of therapy and medical attention. Results: One thousand patients were included and 905 questionnaires evaluated. Most patients felt protected and better since the beginning of therapy (71.5% and 61.5%, respectively). Patient characteristics associated with negative perceptions were; female sex (Odds Ratio [OR] 1.58, 95% Confidence Interval [CI] 1.06-2.36, p = 0.01); patients with less than 1 year of therapy (OR 2.16, 95% CI 1.34-3.48, p = 0.006); those not satisfied with medical attention (OR 2.86, 95% CI 1.53-5.18, p = 0.0001); and those that modified their lifestyle (OR 2.75,95% CI 1.49-4.91, p = 0.0002). Patients with a lower bleeding risk (INR 2.0-3.0) had more negative perceptions than those with a higher risk. Patients with negative perceptions achieved the lowest score in the SF-36 survey. Haemorrhages did not affect patients' perception or QOL. Conclusions: Patients' perceptions correlated with QOL. We were able to identify patient characteristics associated with poor QOL and thus the group of patients whose negative perceptions most warranted special attention from their clinicians. © 2005 Librapharm Limited.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Librapharm/informa Healthcare
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Anticoagulants
dc.subject
Atrial Fibrillation
dc.subject
Bleeding
dc.subject
Heart Valve Prostheses
dc.subject
Quality of Life
dc.subject
Sf-36 Survey
dc.subject.classification
Medicina Critica y de Emergencia
dc.subject.classification
Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Patients' perceptions regarding oral anticoagulation therapy and its effect on quality of life
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-12T17:28:18Z
dc.journal.volume
21
dc.journal.number
7
dc.journal.pagination
1085-1090
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Casais, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina
dc.description.fil
Fil: Meschengieser, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina
dc.description.fil
Fil: Sánchez Luceros, Analía Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina
dc.description.fil
Fil: Lazzari, María Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Academia Nacional de Medicina de Buenos Aires; Argentina
dc.journal.title
Current Medical Research And Opinion.
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1185/030079905X50624
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1185/030079905X50624
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