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dc.contributor.author
Franchini, Lucia Florencia  
dc.contributor.author
Pollard, Katherine S.  
dc.date.available
2018-11-23T21:53:27Z  
dc.date.issued
2017-10-02  
dc.identifier.citation
Franchini, Lucia Florencia; Pollard, Katherine S.; Human evolution: The non-coding revolution; BioMed Central; Bmc Biology; 15; 1; 2-10-2017; 1-12  
dc.identifier.issn
1741-7007  
dc.identifier.uri
http://hdl.handle.net/11336/65096  
dc.description.abstract
What made us human? Gene expression changes clearly played a significant part in human evolution, but pinpointing the causal regulatory mutations is hard. Comparative genomics enabled the identification of human accelerated regions (HARs) and other human-specific genome sequences. The major challenge in the past decade has been to link diverged sequences to uniquely human biology. This review discusses approaches to this problem, progress made at the molecular level, and prospects for moving towards genetic causes for uniquely human biology.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
BioMed Central  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Evolution  
dc.subject
Human  
dc.subject
Brain  
dc.subject
Primates  
dc.subject.classification
Otras Ciencias Biológicas  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Human evolution: The non-coding revolution  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-10-23T20:18:48Z  
dc.journal.volume
15  
dc.journal.number
1  
dc.journal.pagination
1-12  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Franchini, Lucia Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina  
dc.description.fil
Fil: Pollard, Katherine S.. University of California; Estados Unidos  
dc.journal.title
Bmc Biology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1186/s12915-017-0428-9  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0428-9  

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