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dc.contributor.author
Gouw, Marc
dc.contributor.author
Michael, Sushama
dc.contributor.author
Sámano Sánchez, Hugo
dc.contributor.author
Kumar, Manjeet
dc.contributor.author
Zeke, András
dc.contributor.author
Lang, Benjamin
dc.contributor.author
Bely, Benoit
dc.contributor.author
Chemes, Lucia Beatriz
dc.contributor.author
Davey, Norman E
dc.contributor.author
Deng, Ziqi
dc.contributor.author
Diella, Francesca
dc.contributor.author
Gürth, Clara Marie
dc.contributor.author
Huber, Ann Kathrin
dc.contributor.author
Kleinsorg, Stefan
dc.contributor.author
Schlegel, Lara S.
dc.contributor.author
Palopoli, Nicolás
dc.contributor.author
Roey, Kim V
dc.contributor.author
Altenberg, Brigitte
dc.contributor.author
Reményi, Attila
dc.contributor.author
Dinkel, Holger
dc.contributor.author
Gibson, Toby J.
dc.date.available
2018-11-14T14:27:24Z
dc.date.issued
2018-01
dc.identifier.citation
Gouw, Marc; Michael, Sushama; Sámano Sánchez, Hugo; Kumar, Manjeet; Zeke, András; et al.; The eukaryotic linear motif resource - 2018 update; Oxford University Press; Nucleic Acids Research; 46; D1; 1-2018; D428-D434
dc.identifier.issn
0305-1048
dc.identifier.uri
http://hdl.handle.net/11336/64451
dc.description.abstract
Short linear motifs (SLiMs) are protein binding modules that play major roles in almost all cellular processes. SLiMs are short, often highly degenerate, difficult to characterize and hard to detect. The eukaryotic linear motif (ELM) resource (elm.eu.org) is dedicated to SLiMs, consisting of a manually curated database of over 275 motif classes and over 3000 motif instances, and a pipeline to discover candidate SLiMs in protein sequences. For 15 years, ELM has been one of the major resources for motif research. In this database update, we present the latest additions to the database including 32 new motif classes, and new features including Uniprot and Reactome integration. Finally, to help provide cellular context, we present some biological insights about SLiMs in the cell cycle, as targets for bacterial pathogenicity and their functionality in the human kinome.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Oxford University Press
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Short Linear Motifs
dc.subject
Slims
dc.subject
Elm
dc.subject
Database Issue
dc.subject.classification
Ciencias de la Información y Bioinformática
dc.subject.classification
Ciencias de la Computación e Información
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
The eukaryotic linear motif resource - 2018 update
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-22T21:51:28Z
dc.identifier.eissn
1362-4962
dc.journal.volume
46
dc.journal.number
D1
dc.journal.pagination
D428-D434
dc.journal.pais
Reino Unido
dc.journal.ciudad
Oxford
dc.description.fil
Fil: Gouw, Marc. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Michael, Sushama. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Sámano Sánchez, Hugo. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Kumar, Manjeet. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Zeke, András. Hungarian Academy Of Sciences; Hungría
dc.description.fil
Fil: Lang, Benjamin. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Bely, Benoit. Wellcome Trust; Reino Unido
dc.description.fil
Fil: Chemes, Lucia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.description.fil
Fil: Davey, Norman E. Universidad de Dublin; Irlanda
dc.description.fil
Fil: Deng, Ziqi. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Diella, Francesca. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Gürth, Clara Marie. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Huber, Ann Kathrin. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Kleinsorg, Stefan. Universitat Heidelberg; Alemania
dc.description.fil
Fil: Schlegel, Lara S.. Universitat Heidelberg; Alemania
dc.description.fil
Fil: Palopoli, Nicolás. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Roey, Kim V. Universitat Heidelberg; Alemania
dc.description.fil
Fil: Altenberg, Brigitte. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Reményi, Attila. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Dinkel, Holger. European Molecular Biology Laboratory Heidelberg; Alemania
dc.description.fil
Fil: Gibson, Toby J.. European Molecular Biology Laboratory Heidelberg; Alemania
dc.journal.title
Nucleic Acids Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1093/nar/gkx1077
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/nar/article/46/D1/D428/4612965


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