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dc.contributor.author Hergert, Lisandro Yamil
dc.contributor.author Nieto, Marcelo J.
dc.contributor.author Becerra, María Cecilia
dc.contributor.author Albesa, Inés
dc.contributor.author Mazzieri, Maria Rosa
dc.date.available 2018-11-14T13:05:56Z
dc.date.issued 2008-07
dc.identifier.citation Hergert, Lisandro Yamil; Nieto, Marcelo J.; Becerra, María Cecilia; Albesa, Inés; Mazzieri, Maria Rosa; Synthesis of N-benzenesulfonylbenzotriazole derivatives, and evaluation of their antimicrobial activity; Bentham Science Publishers; Letters In Drug Design & Discovery; 5; 5; 7-2008; 313-318
dc.identifier.issn 1570-1808
dc.identifier.uri http://hdl.handle.net/11336/64435
dc.description.abstract A series of benzenesulfonyl compounds, 1a-i, containing a BZT moiety was synthesized and characterized, and their antifungal and antibacterial activities were investigated. Compounds la and 1d showed the highest activity against Escherichia coli ATCC 25922; in addition la presented bactericidal activity against E. coli and Staphylococcus aureus at 8.6 mM. The ability of la to generate superoxide anion (O2-) was measured and it showed more stimuli in S. aureus compared to sulfafhiazole, indicating that 1a can be involved in oxidative stress of bacteria. None of the compounds inhibited the growth of the dermatophytes strains at the tested concentration (250 μg/ml). © 2008 Bentham Science Publishers Ltd.
dc.format application/pdf
dc.language.iso eng
dc.publisher Bentham Science Publishers
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject ANTIBACTERIAL
dc.subject ANTIFUNGAL
dc.subject BENZENESULFONYL
dc.subject BENZOTRIAZOLE
dc.subject.classification Otras Ciencias Biológicas
dc.subject.classification Ciencias Biológicas
dc.subject.classification CIENCIAS NATURALES Y EXACTAS
dc.title Synthesis of N-benzenesulfonylbenzotriazole derivatives, and evaluation of their antimicrobial activity
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2018-11-12T13:47:20Z
dc.identifier.eissn 1875-628X
dc.journal.volume 5
dc.journal.number 5
dc.journal.pagination 313-318
dc.journal.pais Estados Unidos
dc.journal.ciudad Oak Park
dc.description.fil Fil: Hergert, Lisandro Yamil. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina
dc.description.fil Fil: Nieto, Marcelo J.. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Southern Illinois University; Estados Unidos
dc.description.fil Fil: Becerra, María Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
dc.description.fil Fil: Albesa, Inés. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina
dc.description.fil Fil: Mazzieri, Maria Rosa. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina
dc.journal.title Letters In Drug Design & Discovery
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/82876/article
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.2174/157018008784912108
dc.conicet.fuente individual


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)