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dc.contributor.author
Hergert, Lisandro Yamil
dc.contributor.author
Nieto, Marcelo J.
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Becerra, María Cecilia
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Albesa, Inés
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Mazzieri, Maria Rosa
dc.date.available
2018-11-14T13:05:56Z
dc.date.issued
2008-07
dc.identifier.citation
Hergert, Lisandro Yamil; Nieto, Marcelo J.; Becerra, María Cecilia; Albesa, Inés; Mazzieri, Maria Rosa; Synthesis of N-benzenesulfonylbenzotriazole derivatives, and evaluation of their antimicrobial activity; Bentham Science Publishers; Letters In Drug Design & Discovery; 5; 5; 7-2008; 313-318
dc.identifier.issn
1570-1808
dc.identifier.uri
http://hdl.handle.net/11336/64435
dc.description.abstract
A series of benzenesulfonyl compounds, 1a-i, containing a BZT moiety was synthesized and characterized, and their antifungal and antibacterial activities were investigated. Compounds la and 1d showed the highest activity against Escherichia coli ATCC 25922; in addition la presented bactericidal activity against E. coli and Staphylococcus aureus at 8.6 mM. The ability of la to generate superoxide anion (O2-) was measured and it showed more stimuli in S. aureus compared to sulfafhiazole, indicating that 1a can be involved in oxidative stress of bacteria. None of the compounds inhibited the growth of the dermatophytes strains at the tested concentration (250 μg/ml). © 2008 Bentham Science Publishers Ltd.
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application/pdf
dc.language.iso
eng
dc.publisher
Bentham Science Publishers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Antibacterial
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Antifungal
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Benzenesulfonyl
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Benzotriazole
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Otras Ciencias Biológicas
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Synthesis of N-benzenesulfonylbenzotriazole derivatives, and evaluation of their antimicrobial activity
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-11-12T13:47:20Z
dc.identifier.eissn
1875-628X
dc.journal.volume
5
dc.journal.number
5
dc.journal.pagination
313-318
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Oak Park
dc.description.fil
Fil: Hergert, Lisandro Yamil. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina
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Fil: Nieto, Marcelo J.. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Southern Illinois University; Estados Unidos
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Fil: Becerra, María Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
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Fil: Albesa, Inés. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina
dc.description.fil
Fil: Mazzieri, Maria Rosa. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina
dc.journal.title
Letters In Drug Design & Discovery
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/82876/article
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.2174/157018008784912108
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