Artículo
Synthesis of optically active derivatives of bicyclic chiral diols with C2 symmetry
Fecha de publicación:
01/2011
Editorial:
Pergamon-Elsevier Science Ltd
Revista:
Tetrahedron: Asymmetry
ISSN:
0957-4166
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
This paper reports efficient procedures for the preparation of optically active dibromide, diazide, diamine, and unsaturated diesters derived from a chiral bicyclic diol with C2 symmetry namely (11R,12R)-9,10-dihydro- 9,10-ethaneanthracene-11,12-dimethanol 3. Esterification of 3 with saturated and unsaturated carboxylic acids and acids chlorides leads to the corresponding normal-, olefinic- and acetylenic diesters in average yields of 81%. Also more efficient techniques for the preparation of starting diol 3 in higher yields as well as for a very simple separation of DCU (N,N′-dicyclohexylurea) from reactions carried out following the DCC/DMAP method are described. © 2010 Elsevier Ltd. All rights reserved.
Palabras clave:
Bicyclic Chiral Diols
,
C2 Symmetry
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(INQUISUR)
Articulos de INST.DE QUIMICA DEL SUR
Articulos de INST.DE QUIMICA DEL SUR
Citación
Zacconi, Flavia Cristina Milagro; Koll, Liliana Cristina; Podestá, Julio Cesar; Synthesis of optically active derivatives of bicyclic chiral diols with C2 symmetry; Pergamon-Elsevier Science Ltd; Tetrahedron: Asymmetry; 22; 1; 1-2011; 40-46
Compartir
Altmétricas