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dc.contributor.author
Estébanez, Sandra
dc.contributor.author
Thomas, Andrés Héctor
dc.contributor.author
Lorente, Carolina
dc.date.available
2018-11-06T19:07:42Z
dc.date.issued
2017-11
dc.identifier.citation
Estébanez, Sandra; Thomas, Andrés Héctor; Lorente, Carolina; Deoxythymidine–Pterin Fluorescent Adduct Formation through a Photosensitized Process; Wiley VCH Verlag; Chemphyschem; 19; 3; 11-2017; 300-306
dc.identifier.issn
1439-4235
dc.identifier.uri
http://hdl.handle.net/11336/63805
dc.description.abstract
A new fluorescent compound was isolated from UVA-irradiated aqueous solutions containing pterin (Ptr) and 2′deoxythymidine (dT) in anaerobic conditions. Pterins are widespread in living systems in small amounts, but they are accumulated in some pathological situations. Under UVA radiation, pterins are photochemically active, fluorescent, and photosensitize the generation of singlet oxygen [1O2(1Δg)]. The isolated compound was structurally characterized by using liquid chromatography coupled to tandem mass spectrometry, and its photophysical properties were studied with the time-correlated single-photon-counting technique. The molecular weight and the analysis of the fragmentation correspond to a molecule where the pterinic moiety is attached to the thymine nucleobase. The product exhibits photophysical properties similar to those of Ptr, including relatively high fluorescence and 1O2 production quantum yields.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley VCH Verlag
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
2″-Deoxythymidine
dc.subject
Electron Transfer
dc.subject
Photosensitization
dc.subject
Pterins
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Radicals
dc.subject.classification
Otras Ciencias Químicas
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Deoxythymidine–Pterin Fluorescent Adduct Formation through a Photosensitized Process
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-22T22:32:55Z
dc.journal.volume
19
dc.journal.number
3
dc.journal.pagination
300-306
dc.journal.pais
Alemania
dc.journal.ciudad
Weinheim
dc.conicet.avisoEditorial
This is the peer reviewed version of the following article: S. Estébanez, A. H. Thomas, C. Lorente, ChemPhysChem 2018, 19, 300, which has been published in final form at https://doi.org/10.1002/cphc.201701101 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
dc.description.fil
Fil: Estébanez, Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
dc.description.fil
Fil: Thomas, Andrés Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
dc.description.fil
Fil: Lorente, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
dc.journal.title
Chemphyschem
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/cphc.201701101
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/cphc.201701101
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