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dc.contributor.author
Gloriani, Alejandro H.
dc.contributor.author
Arranz, Isabel
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Matezanz, Beatriz
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Issolio, Luis Alberto
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Menéndez, José Antonio
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Mar, Santiago
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Galindo, Alicia
dc.contributor.author
Aparicio, Juan Antonio
dc.date.available
2018-10-25T20:00:31Z
dc.date.issued
2017-02
dc.identifier.citation
Gloriani, Alejandro H.; Arranz, Isabel; Matezanz, Beatriz; Issolio, Luis Alberto; Menéndez, José Antonio; et al.; Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results; Open Access Text; New Frontiers in Ophthalmology; 3; 1; 2-2017; 1-5
dc.identifier.issn
2397-2092
dc.identifier.uri
http://hdl.handle.net/11336/63104
dc.description.abstract
PURPOSE: To measure the sensitivity of small retinal areas by reducing the influence of the adaptation state of the rest of the retina. To assess the functional behaviour of the retina of several patients affected by different types of retinitis pigmentosa (RP). METHODS: A prospective study was performed. Five eyes of patients with retinal diseases and different genetic mutations were studied at the University of Valladolid: three typical RP, one cone rod dystrophy (CRD) and one Bardet-Biedl syndrome (BBS). One of the RP patients was analysed again 18 months after the first measurements. A two-maxwellian view optical arrangement was used to measure the luminance thresholds of retinal areas 1 deg sized under dark and low photopic adaptation conditions. Linear regression fits of these threshold contrasts as a function of the eccentricity were used to compare the sensitivity of the patients with respect to the control group.RESULTS: The slopes of the linear fits of the other typical RP patients were higher than those of the control group. The parameters of the linear fits of the RP patient measured twice changed significantly with time. CONCLUSIONS: The designed psychophysical method provides, in all cases, coherent results with the expected ones according to the genetic mutation of the patients. The technique seems to be very sensitive to changes in the retinal response. It can be easily incorporated as a technical complement to the traditional perimetry.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Open Access Text
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Retinitis Pigmentosa
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Cone-Rod Distrophy
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Photoreceptors
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Psychophysics
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Oftalmología
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Small-field perimetry applied to different types of retinitis pigmentosa: preliminary results
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-23T17:51:16Z
dc.journal.volume
3
dc.journal.number
1
dc.journal.pagination
1-5
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Gloriani, Alejandro H.. Universidad de Valladolid. Facultad de Ciencias; España
dc.description.fil
Fil: Arranz, Isabel. Universidad de Valladolid. Facultad de Ciencias; España
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Fil: Matezanz, Beatriz. Universidad de Valladolid. Facultad de Ciencias; España
dc.description.fil
Fil: Issolio, Luis Alberto. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Laboratorio de Luminotecnia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; Argentina
dc.description.fil
Fil: Menéndez, José Antonio. Universidad de Valladolid. Facultad de Ciencias; España
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Fil: Mar, Santiago. Universidad de Valladolid. Facultad de Ciencias; España
dc.description.fil
Fil: Galindo, Alicia. Hospital Universitario Río Ortega. Valladolid; España
dc.description.fil
Fil: Aparicio, Juan Antonio. Universidad de Valladolid. Facultad de Ciencias; España
dc.journal.title
New Frontiers in Ophthalmology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.15761/NFO.1000152
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.oatext.com/field-perimetry-applied-to-different-types-of-retinitis-pigmentosa-preliminary-results.php
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