Artículo
HAC1 and HAF1 histone acetyltransferases have different roles in UV-B responses in arabidopsis
Fecha de publicación:
07/2017
Editorial:
Frontiers Research Foundation
Revista:
Frontiers in Plant Science
ISSN:
1664-462X
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Arabidopsis has 12 histone acetyltransferases grouped in four families: the GNAT/HAG, the MYST/HAM, the p300/CBP/HAC and the TAFII250/HAF families. We previously showed that ham1 and ham2 mutants accumulated higher damaged DNA after UV-B exposure than WT plants. In contrast, hag3 RNA interference transgenic plants showed less DNA damage and lower inhibition of plant growth by UV-B, and increased levels of UV-B-absorbing compounds. These results demonstrated that HAM1, HAM2, and HAG3 participate in UV-B-induced DNA damage repair and signaling. In this work, to further explore the role of histone acetylation in UV-B responses, a putative function of other acetyltransferases of the HAC and the HAF families was analyzed. Neither HAC nor HAF acetyltrasferases participate in DNA damage and repair after UV-B radiation in Arabidopsis. Despite this, haf1 mutants presented lower inhibition of leaf and root growth by UV-B, with altered expression of E2F transcription factors. On the other hand, hac1 plants showed a delay in flowering time after UV-B exposure and changes in FLC and SOC1 expression patterns. Our data indicate that HAC1 and HAF1 have crucial roles for in UV-B signaling, confirming that, directly or indirectly, both enzymes also have a role in UV-B responses.
Palabras clave:
Arabidopsis
,
Cbp
,
Hac
,
Haf
,
Histone Acetyltransferases
,
Tafii250
,
Uv-B
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CEFOBI)
Articulos de CENTRO DE EST.FOTOSINTETICOS Y BIOQUIMICOS (I)
Articulos de CENTRO DE EST.FOTOSINTETICOS Y BIOQUIMICOS (I)
Citación
Fina, Julieta Paola; Masotti, Fiorella; Rius, Sebastian Pablo; Crevacuore, Franco; Casati, Paula; HAC1 and HAF1 histone acetyltransferases have different roles in UV-B responses in arabidopsis; Frontiers Research Foundation; Frontiers in Plant Science; 8; 7-2017; 1-17
Compartir
Altmétricas