Artículo

Phenotypic and molecular evaluation of echinocandin susceptibility of Candida glabrata, Candida bracarensis, and Candida nivariensis strains isolated during 30 years in Argentina

Morales López, Soraya; Dudiuk, Catiana BeatrizIcon ; Vivot, Walter; Szusz, Wanda; Córdoba, Susana Beatríz; Garcia, Guillermo ManuelIcon
Fecha de publicación: 07/2017
Editorial: American Society for Microbiology
Revista: Antimicrobial Agents and Chemotherapy
ISSN: 0066-4804
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The echinocandin susceptibilities of 122 Candida glabrata complex strains (including 5 Candida nivariensis and 3 Candida bracarensis strains) were evaluated by microdilution and compared with the results from a molecular tool able to detect FKS mutations. No echinocandin resistance was detected. The PCR results coincide with the MIC data in 99.25% of the cases (1 C. glabrata strain was misidentified as resistant) but were 20 h faster. C. nivariensis FKS genes were sequenced and showed differences with C. glabrata FKS genes.
Palabras clave: Candida Bracarensis , Candida Glabrata Species Complex , Candida Nivariensis , Echinocandin Resistance , Hot Spot
 
Archivos asociados
Thumbnail
 
Tamaño: 227.3Kb
Formato: PDF
.
Licencia
info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/58688
DOI: https://dx.doi.org/10.1128/AAC.00170-17
URL: https://aac.asm.org/content/61/7/e00170-17
Colecciones
Articulos(CCT - SANTA FE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Citación
Morales López, Soraya; Dudiuk, Catiana Beatriz; Vivot, Walter; Szusz, Wanda; Córdoba, Susana Beatríz; et al.; Phenotypic and molecular evaluation of echinocandin susceptibility of Candida glabrata, Candida bracarensis, and Candida nivariensis strains isolated during 30 years in Argentina; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 61; 7; 7-2017; 1-4
Compartir
Altmétricas